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Models

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Mice

hGLP1R

Strain Name：C57BL/6Smoc-Glp1rtm2(hGLP1R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200220
Validation Data：Presence  |  Publications：1piece

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

Mice

hCTLA-4

Strain Name：C57BL/6Smoc-Ctla4tm1(hCTLA4) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00014
Validation Data：Presence

The endogenous mouse Ctal4 gene was replaced by human CTLA4 gene. While hCTLA4(2)(Stock No.NM-HU-190038) mice function similarly to hCTLA4 mice,for more detailed information please contact our technical advisor.

Mice

hCCR8(BALB/c)

Strain Name：BALB/cAnSmoc-Ccr8tm1(hCCR8)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000048
Validation Data：Presence

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene.

Mice

Abcg2-KO

Strain Name：C57BL/6Smoc-Abcg2em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18013
Validation Data：Presence

Exon3-5 of Abcg2 gene were deleted to generate Abcg2 knockout mice.

Mice

hTTR

Strain Name：C57BL/6Smoc-Ttrtm1(hTTR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225087
Validation Data：Presence

The endogenous mouse Ttr gene was replaced by human TTR gene.

Mice

hALB

Strain Name：C57BL/6Smoc-Albtm3(ALB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200003
Validation Data：Presence

The endogenous mouse Alb gene was replaced by human ALB gene.

Mice

hTLR8

Strain Name：C57BL/6Smoc-Tlr8tm2(TLR8)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190044
Validation Data：Presence

The endogenous mouse Tlr8 gene was replaced by human TLR8 gene.

Mice

hCD3E

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00114
Validation Data：Presence

The endogenous mouse Cd3e gene was replaced by human CD3E gene . While hCD3E(2)(Stock No.NM-HU-210023) mice function similarly to hCD3E mice,for more detailed information please contact our technical advisor.

Mice

hCRBN

Strain Name：C57BL/6Smoc-Crbntm1(hCRBN)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225071
Validation Data：Presence

The endogenous mouse Crbn gene was replaced by human CRBN gene.

Mice

hCD27(2)

Strain Name：C57BL/6Smoc-Cd27tm3(hCD27)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190035
Validation Data：Presence

The endogenous mouse Cd27 gene was replaced by human CD27 gene. While hCD27 mice(Stock No.NM-HU-00093）have been pulled from shelves for some reasons.

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