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Models

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Mice

Pdx1-2A-Cre

Strain Name：C57BL/6Smoc-Pdx1em(2A-Cre)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225082

2A-Cre expression cassette was knocked into the Pdx1 gene .

Mice

Vav1-2A-Cre

Strain Name：C57BL/6Smoc-Vav1em1(2A-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-233228

The 2A-Cre expression cassette was knocked into the Vav1 gene stop codon site.

Mice

Cd4-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Cd4em5(IRES-DTREGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190121

A IRES-DTREGFP expression cassette was knocked into the Cd4 gene stop codon site.

Mice

hFCRN

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Fcgrtem1/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00109

This FcRn humanized strain is established by mating endogenous mouse Fcgrt gene Knockout mice with R26-hFcRn(FCGRT) Knock-in mice. These FcRn humanized mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations. While hFCRN(2)(Stock No.NM-HU-190070) and hFCRN(3)(Stock No.NM-HU-2000032）mice function similarly to hFCRN mice,for more detailed information please contact our technical advisor.

Mice

Pdcd1-Flox

Strain Name：C57BL/6Smoc-Pdcd1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-210063

These mice carry loxP sites flanking exon 2-4 of Pdcd1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Pdcd1 gene.

Mice

Arg1-Flox

Strain Name：C57BL/6Smoc-Arg1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200062

These mice carry loxP sites flanking exon 5-8 of Arg1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Arg1 gene.

Mice

Eef2kmt-Flox

Strain Name：C57BL/6Smoc-Eef2kmtem1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-234542

These strains carry loxP sites flanking exon 3-6 of Eef2kmt gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Eef2kmt gene.

Mice

Atp4b-IRES-CreERT2

Strain Name：C57BL/6Smoc-Atp4bem1(IRES-CreERT2-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210118

An IRES-CreERT2-WPRE-pA expression cassette was knocked into the Atp4b gene stop codon site. Besides, An IRES-CreERT2 expression cassette were knock into the Bhlha15 gene stop codon site to generate Atp4b-IRES-CreERT2(2)(Stock No. NM-KI-210119) mice.

Mice

Il1b-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1bem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00010

A Luciferase-2A-EGFP-pA cassette was inserted at ATG site of mouse Il1b gene. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il1b.

Mice

hIL17A/hIL17F

Strain Name：C57BL/6Smoc-Il17atm1(hIL17A)Il17fem2(hIL17F)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200281

The endogenous mouse Il17a&Il17f genes were replaced by human IL17A&IL17F gene.

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