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Models

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Mice

hSIRPA(2)/hCD47/hPD-L1

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274tm1(hCD274)Cd47tm1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000095

hPD-L1(NM-HU-00062),hCD47(NM-HU-00050) was crossed with hSIRPA(2) (NM-HU-18015) to generate hSIRPA(2)/hCD47/hPD-L1.

Mice

hIL4

Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190071
Validation Data：Presence

The endogenous mouse Il4 gene was completely or partially replaced by human IL4 gene via ESC targeting.

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA-4

Strain Name：C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-220070

The Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA4 mouse model was obtained by deleting sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hPD-1/hCTLA4(NM-HU-00079) mouse.

Mice

hPD-L1/hSIRPA(2)

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274tm1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000099

hPD-L1(NM-HU-00062) was crossed with hSIRPA(2)(NM-HU-18015) to generate hPD-L1/hSIRPA(2).

Mice

hPD-1/hCD27(2)

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd27tm2(hCD27)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000096

hPD-1(NM-HU-00015) was crossed with hCD27(2)(NM-HU-190035) to generate hPD-1/hCD27(2).

Mice

R26-CAG-hFcRn

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-hFcRn)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00081

A human FCGRT expression cassette was knocked in mouse Rosa26 loci.

Mice

hTLR8/Lyz2-DTREGFP

Strain Name：C57BL/6Smoc-Lyz2tm3(IRES-DTREGFP)Tlr8tm2(TLR8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200259

NM-KI-190041 was crossed with NM-HU-190044 to generate hTLR8/Lyz2-IRES-DTREGFP mice.

Mice

Adgrg6-Flox

Strain Name：B6;129S-Adgrg6tm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00096

These mice carry loxP sites flanking exon 2. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Drg1-Flox

Strain Name：C57BL/6Smoc-Drg1em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Drg1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Drg1 gene.

Mice

Drg2-Flox

Strain Name：C57BL/6Smoc-Drg2em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Drg2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Drg2 gene.

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