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Models

About 355 results
Mice

hICOS(2)

Strain Name：C57BL/6Smoc-Icostm2(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190030
Validation Data：Presence

The endogenous mouse Icos gene was replaced by human ICOS gene. While hICOS(Stock No.NM-HU-00052) mice function similarly to hICOS(2) mice,for more detailed information please contact our technical advisor.

Mice

hIL5/hIL5R(2)

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Il5ratm2(hIL5RA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220010
Validation Data：Presence

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(3)(Stock No.NM-HU-220011) function similarly to hIL5/hIL5R(2) mice, for more detailed information please contact our technical advisor.

Mice

hIL2

Strain Name：C57BL/6Smoc-Il2tm3(hIL2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190048
Validation Data：Presence

The endogenous mouse Il2 gene was replaced by human IL2 gene.

Mice

hIL5/hIL5R(3)

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Il5ratm3(hIL5RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220011
Validation Data：Presence

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.

Mice

hIL3/hCSF2

Strain Name：C57BL/6Smoc-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190065
Validation Data：Presence

The endogenous mouse Il3 and Csf2 gene was replaced by human IL3 and CSF2 gene.

Mice

hLAIR1

Strain Name：C57BL/6Smoc-Lair1tm2(LAIR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000011

The endogenous mouse Lair1 gene was replaced by human LAIR1 gene .

Mice

Trp53-KO

Strain Name：B6.129-Trp53tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00011

A neo cassette replaces exons 2-11,including the start codon,of Trp53 (transformation related protein 53).Null homozygotes show high, early-onset tumor incidence;some have persistent hyaloid vasculature and cataracts.

Mice

hIL6

Strain Name：C57BL/6Smoc-Il6tm1(hIL6)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18017

This IL6 humanized mouse model was established by replacing the mouse Il6 gene coding exon1-5 and introns with the human IL6 corresponding sequence by homologous recombination via ES cell targeting.

Mice

hPD-L1/hCD28

Strain Name：C57BL/6Smoc-Cd274tm1(hPD-L1)Cd28tm2(hCD28)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210019

hPD-L1(NM-HU-00062) was crossed with hCD28(NM-HU-190011) to generate hPD-L1/hCD28 mice

Mice

hHER2

Strain Name：C57BL/6Smoc-Erbb2tm1(hERBB2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200115
Validation Data：Presence

The endogenous mouse Erbb2 gene was replaced by human ERBB2 gene.

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