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Models

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Mice

Slc10a1-KO(2)

Strain Name：C57BL/6Smoc-Slc10a1em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200760

Slc10a1-KO(2) mice(Stock No.NM-KO-200760）carry a knockout allele derived from the targeted deletion of exon 2. While Slc10a1-KO mice (Stock No.NM-KO-190371) carrying the exon 3 deletion.

Mice

Ptgir-KO(2)

Strain Name：C57BL/6Smoc-Ptgirem2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210302

Prkaa1-KO(2) mice (Stock No.NM-KO-210302） carry a knockout allele derived from the targeted deletion of exon 1. While Ptgir-KO mice (Stock No.NM-KO-191022）carrying the exon 1-2 deletion.

Mice

Sirt7-KO(2)

Strain Name：C57BL/6Smoc-Sirt7em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210262

Sirt7-KO(2) mice(Stock No.NM-KO-210262）carry a knockout allele derived from the targeted deletion of exon 4-9. While Sirt7-KO mice (Stock No.NM-KO-210229) carrying the exon 6-9 deletion.

Mice

Snx3-KO(2)

Strain Name：C57BL/6Smoc-Snx3emSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210172

Snx3-KO(2) mice(Stock No.NM-KO-210172） carry a knockout allele derived from the targeted deletion of exon 3. While Snx3-KO mice(Stock No.NM-KO-201912）carrying the exon 2-3 deletion. It has been reported in the literature that homozygous for this gene knockout will die in the embryonic stage.

Mice

Sept5-KO(2)

Strain Name：C57BL/6Smoc-Sept5emSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-210168

Sept5-KO(2) mice (Stock No.NM-KO-210168) carry a knockout allele derived from the targeted deletion of exon 3-8. While Ptgs2-KO mice(Stock No.NM-KO-191030）carrying the exon 2 deletion.

Mice

Hif3a-KO(2)

Strain Name：C57BL/6Smoc-Hif3aem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-210081

Hif3a-KO(2) mice(Stock No.NM-KO-210081) carry a knockout allele derived from the targeted deletion of exon 7-8. While Hif3a-KO mice(Stock No.NM-KO-191062) carrying the exon 3 deletion.

Mice

Foxn1-KO(BALB/c)

Strain Name：BALB/cAnSmoc-Foxn1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200735

Foxn1-KO(BALB/c) mice (Stock No.NM-KO-200735）carry a knockout allele derived from the targeted deletion of exon 5. While Foxn1-KO(BALB/c,2) mice (Stock No.NM-KO-205001）mice carrying the exon 2-9 deletion.

Mice

Thy1-KO(2)

Strain Name：C57BL/6Smoc-Thy1em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200714

Thy1-KO(2) mice(Stock No.NM-KO-NM-KO-200714）carry a knockout allele derived from the targeted deletion of exon 3-4. While Thy1-KO mice (Stock No.NM-KO-190162) carrying the exon 2-4 deletion.

Mice

Foxn1-KO(BALB/c,2)

Strain Name：BALB/cAnSmoc-Foxn1em3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-205001

Foxn1-KO(BALB/c,2) mice (Stock No.NM-KO-205001）carry a knockout allele derived from the targeted deletion of exon 2-9. While Foxn1-KO(BALB/c) mice (Stock No.NM-KO-200735）mice carrying the exon 5 deletion.

Mice

F9-KO

Strain Name：C57BL/6Smoc-F9em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18046
Validation Data：Presence  |  Publications：1piece

The F9 gene is located on the X chromosome. In this F9 knockout mouse model, gRNAs were designed targeting Exon8 of F9 gene via CRISPR gene editing technology. Loss of F9 caused coagulopathy in mice. Mice that are homozygous for F9 knockout are viable, fertile and normal in size. Normal fighting in the cage may cause bleeding or even death due to massive internal hemorrhaging. After the tail cutting, wounds must be cauterized to prevent homozygous knockout mice from blood loss and death. This strain is a powerful model for studying coagulopathy, gene therapy methods and function of factor IX mutations. F9-KO mice (Stock No.NM-KO-18046）carry a knockout allele derived from the targeted deletion of exon 8. While F9-KO(2) mice (Stock No.NM-KO-200607) carrying the exon 1-8 deletion.

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