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Mice

Slc6a11-CreERT2

Strain Name:C57BL/6Smoc-Slc6a11em1(CreERT2-polyA(SV40)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200130

A CreERT2-polyA expression cassette was knocked into the Slc6a11 gene start codon site. Slc6a11 encodes GAT3 (Gabt4), a sodium-dependent transporter that uptakes the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which ends the GABA neurotransmission. When Slc6a11-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLC6A11positive cells. Defects in Slc6a11 may result in epilepsy or behavioral and intellectual defects.

Mice

Myf6-CreERT2

Strain Name:C57BL/6Smoc-Myf6em1(CreERT2-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200125

A CreERT2-pA expression cassette was knocked into the Myf6 gene start codon site. Myf6 (myogenic factor 6) is a DNA-binding protein involved in muscle development. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Myf6.

Mice

Nos1-CreERT2

Strain Name:C57BL/6Smoc-Nos1em1(CreERT2-SV40polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200091

A CreERT2-SV40polyA expression cassette was knocked into the Nos1 gene start codon site.

Mice

Tnni3-dCreERT2

Strain Name:C57BL/6Smoc-Tnni3em1(rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200014

A rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA expression cassette was knocked into the Tnni3 gene start codon site.

Mice

Prom1-CreERT2

Strain Name:C57BL/6Smoc-Prom1em1(CreERT2-PolyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200169

A CreERT2-PolyA expression cassette was knocked into the Prom1 gene start codon site. Prom1 encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. When these Prom1-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Prom1 expressing cells.

Mice

Sox2-CreERT2

Strain Name:C57BL/6Smoc-Sox2em1(CreERT2-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200084

The coding region of Sox2 gene was replaced by a CreERT2-polyA expression cassette.

Mice

Cx3cr1-CreERT2

Strain Name:C57BL/6Smoc-Cx3cr1em1(creERT2-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200157

A creERT2-WPRE-polyA expression cassette was knocked into the Cx3cr1 gene start codon site.

Mice

Msx1-CreERT2

Strain Name:C57BL/6Smoc-Msx1em1(CreERT2-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200153

A CreERT2-WPRE-polyA expression cassette was knocked into the Msx1 gene start codon site.

Mice

Lyz2-CreERT2-IRES-EGFP

Strain Name:C57BL/6Smoc-Lyz2em2(CreERT2-IRES-EGFP)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18047

A Kozak-CreERT2-IRES-EGFP expression cassette was knocked into the Lyz2 gene start codon site by homologous recombination.

Mice

Id2-CreERT2

Strain Name:C57BL/6Smoc-Id2em1(CreERT2-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200155

A CreERT2-WPRE-polyA expression cassette was knocked into the Id2 gene start codon site.

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