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Models

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Mice

Cdh16-CreERT2

Strain Name:C57BL/6Smoc-Cdh16em(Kozak-CreERT2)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-225084
Validation Data:Presence

Kozak-CreERT2 expression cassette was knocked into the Cdh16 gene .

Mice

Piezo1-CreERT2

Strain Name:C57BL/6Smoc-Piezo1tm2(CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18048

This tamoxifen-inducing Piezo1-CreERT2 tool mouse model was established by inserting a 2A-CreERT2 co-expression cassette into the Piezo1 gene stop codon site .

Mice

Notch1-CreERT2

Strain Name:C57BL/6Smoc-Notch1em1(CreERT2-2xpA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200122
Validation Data:Presence

A CreERT2-2xpA expression cassette was knocked into the Notch1 gene start codon site. Notch1 performs vital cell functions, such as proliferation, differentiation, apoptosis, and stem cell maintenance. When Notch1-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in NOTCH1 positive cells.

Mice

Lyz2-CreERT2-IRES-EGFP

Strain Name:C57BL/6Smoc-Lyz2em2(CreERT2-IRES-EGFP)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18047
Validation Data:Presence

A Kozak-CreERT2-IRES-EGFP expression cassette was knocked into the Lyz2 gene start codon site by homologous recombination.

Mice

Wdfy1-CreERT2

Strain Name:C57BL/6Smoc-Wdfy1em(Kozak-CreERT2-WPRE-pA )Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-220121

Kozak-CreERT2-WPRE-pA expression cassette was knocked into the Wdfy1 gene start codon site.

Mice

Prom1-CreERT2

Strain Name:C57BL/6Smoc-Prom1em1(CreERT2-PolyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200169
Validation Data:Presence

A CreERT2-PolyA expression cassette was knocked into the Prom1 gene start codon site. Prom1 encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. When these Prom1-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Prom1 expressing cells.

Mice

Nos1-CreERT2

Strain Name:C57BL/6Smoc-Nos1em1(CreERT2-SV40polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200091
Validation Data:Presence

A CreERT2-SV40polyA expression cassette was knocked into the Nos1 gene start codon site.

Mice

Cdh6-CreERT2

Strain Name:C57BL/6Smoc-Cdh6em1(CreERT2-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200140

A CreERT2-WPRE-polyA expression cassette was knocked into the Cdh6 gene start codon site.

Mice

Tnni3-dCreERT2

Strain Name:C57BL/6Smoc-Tnni3em1(rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200014

A rox-CreERT2-wpre-polyA-rox-tdTomato-wpre-polyA expression cassette was knocked into the Tnni3 gene start codon site.

Mice

S100b-CreERT2

Strain Name:C57BL/6Smoc-S100bem1(Kozak-CreERT2-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-232677

The Kozak-CreERT2-WPRE-pA expression cassette was knocked into the S100b gene start codon site.

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