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Mice

Wnt5b-IRES-CreERT2-2A-tdTomato

Strain Name：C57BL/6Smoc-Wnt5bem(IRES-CreERT2-P2A-tdTomato)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215083

IRES-CreERT2-P2A-tdTomato expression cassette was knocked into the Wnt5b gene .

Mice

Acan-IRES-CreERT2

Strain Name：C57BL/6Smoc-Acanem1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200143
Validation Data：Presence

A IRES-CreERT2 expression cassette was knocked into the Acan gene stop codon site via CRISPR/Cas9 mediated recombination.

Mice

Avil-2A-CreERT2

Strain Name：C57BL/6Smoc-Avilem1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215035
Validation Data：Presence

2A-CreERT2 expression cassette was knocked into the Avil gene.

Mice

Slco1c1-2A-CreERT2

Strain Name：C57BL/6Smoc-Slco1c1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200262
Validation Data：Presence

2A-CreERT2 expression cassette was knocked into the Slco1c1 gene stop codon site. Slco1c1 encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. When Slco1c1-2A-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLCO1C1 positive cells.

Mice

Scgb1a1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Scgb1a1em1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200129
Validation Data：Presence

A IRES-CreERT2 expression cassette was knocked into the Scgb1a1 gene stop codon site.

Mice

Hopx-IRES-CreERT2

Strain Name：C57BL/6Smoc-Hopxem1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200136
Validation Data：Presence

A IRES-CreERT2 expression cassette was knocked into the Hopx gene stop codon site.

Mice

Nkx2-1-CreERT2

Strain Name：C57BL/6Smoc-Nkx2-1em1(CreERT2-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200123
Validation Data：Presence

A CreERT2-pA expression cassette was knocked into the Nkx2-1 gene start codon site. Nkx2-1, a key molecule in lung development, is expressed in adult bronchial and alveolar type Ⅱ epithelial cells. Besides, Nkx2-1 expression as a prognostic marker is also been applied to lung cancer research including lung adenocarcinoma.

Mice

Lyz2-2A-CreERT2

Strain Name：C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18018
Validation Data：Presence

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

Ncr1-2A-CreERT2

Strain Name：C57BL/6Smoc-Ncr1em4(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200004
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

Sox9-IRES-CreERT2

Strain Name：C57BL/6Smoc-Sox9em(IRES-CreERT2-SV40pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-204996
Validation Data：Presence  |  Publications：1piece

IRES-CreERT2-SV40pA expression cassette was knocked into the Sox9 gene .

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