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Mice

Tagln-Cre

Strain Name:C57BL/6Smoc-Taglnem1(Cre-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200144
Validation Data:Presence

A Cre-WPRE-polyA expression cassette was knocked into the Tagln gene start codon site. This gene encodes a smooth muscle cell-specific cytoskeletal protein. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in vascular smooth muscle cells. In mouse models of atherosclerosis, the gene product may be involved in plaque cell and atherosclerotic lesion formation during atherogenesis.

Mice

Avil-Cre

Strain Name:C57BL/6Smoc-Avilem1(Cre)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-215036
Validation Data:Presence

Cre expression cassette was knocked into the Avil gene.

Mice

Pax8-Cre

Strain Name:C57BL/6Smoc-Pax8em1(Cre-WPRE-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200151
Validation Data:Presence

A Cre-WPRE-polyA expression cassette was knocked into the Pax8 gene start codon site.

Mice

Il17a-Cre

Strain Name:C57BL/6Smoc-Il17aem1(iCre-polyA(SV40))Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200137
Validation Data:Presence

A iCre-polyA expression cassette was knocked into the Il17a gene start codon site. This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying autoimmune inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis.

Mice

Pgr-Cre

Strain Name:C57BL/6Smoc-Pgrem1(iCre-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200117
Validation Data:Presence

A iCre-WPRE-pA expression cassette was knocked into the Pgr gene start codon site.

Mice

Isl1-Cre

Strain Name:C57BL/6Smoc-Isl1em1(iCre-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200126
Validation Data:Presence

A iCre-WPRE-pA expression cassette was knocked into the Isl1 gene start codon site.

Mice

Myf5-Cre

Strain Name:C57BL/6Smoc-Myf5em1(Cre-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200147
Validation Data:Presence

A Cre-WPRE-polyA expression cassette was knocked into the Myf5 gene start codon site. Myogenic factor 5 (Myf5) belongs to the MRF family transcription factors that regulate myogenesis. It is expressed in the skeletal muscle and satellite cells. Severe loss of skeletal muscle following ablation of Myf5-expressing progenitors. This strain is useful in studying the differentiation of skeletal muscle.

Mice

Il7r-Cre

Strain Name:C57BL/6Smoc-Il7rem1(Cre-Wpre-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200306
Validation Data:Presence

Cre-Wpre-pA expression cassette was knocked into the Il7r gene start codon site.

Mice

Opn4-Cre

Strain Name:C57BL/6Smoc-Opn4em1(Cre-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200304
Validation Data:Presence

Cre-WPRE-polyA expression cassette was knocked into the Opn4 gene start codon site. The melanopsin gene (Opn4) encodes a functional photopigment. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying circadian rhythm regulation.

Mice

Slc6a4-Cre

Strain Name:C57BL/6Smoc-Slc6a4em1(iCre-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200115
Validation Data:Presence

A iCre-pA expression cassette was knocked into the Slc6a4 gene start codon site. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. The gene product has been involved in the neurological disorders such as addiction and depression.

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