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Models

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Mice

huHSC-(NMG)

Strain Name：huHSC-(NMG)
Strain State：Repository Live | Cat. NO.：NM-NSG-017

After irradiation, NMG mice are injected with CD34+ hematopoietic stem cells (CD34+ HSC).

Mice

Mycn-TRE-EGFP

Strain Name：B6;129S-Mycntm1(TRE-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00008

A TRE site and a loxp EGFP casette were inserted into introns 1-2 to create a Dox-inducible N-myc gene silence mice.

Mice

Abtb1-KO

Strain Name：B6;129S-Abtb1tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00001

Exon 2 to exon 12 were replaced with Neo cassette.

Mice

Egfr-Flox

Strain Name：C57BL/6Smoc-Egfrem1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00133

These Egfr flox mice possess loxP sites flanking exons 19. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Tnf-KO

Strain Name：C57BL/6Smoc-Tnfem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-00100

Exon2-3 of Tnf gene were targeted to generate the Tnf knockout mice.

Mice

Trp53-R172H

Strain Name：C57BL/6Smoc-Trp53em4(R172H)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18028

These mice carry a p.R172H mutation of Trp53 gene.

Mice

Rb1-Flox

Strain Name：C57BL/6Smoc-Rb1tm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-18012

These mice carry loxP sites flanking exon3 of Rb1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Rb1 gene.

Mice

Tet2-KO

Strain Name：B6;129S-Tet2tm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00127

Exon3 of mouse Tet2 gene was replaced by frt-Pgk-Neo-polyA-frt cassette by homologous recombination.

Mice

Reg3b-Flox

Strain Name：C57BL/6Smoc-Reg3bem1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00128

These mice carry loxP sites flanking exon 3-4 of Reg3b gene.

Mice

Hdac4-KO

Strain Name：C57BL/6Smoc-Hdac4em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00075

Exon 4 was removed.

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