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Mice

Ptf1a-CreERT2

Strain Name：C57BL/6Smoc-Ptf1aem1(CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200118

A CreERT2-WPRE-pA expression cassette was knocked into the Ptf1a gene start codon site.

Mice

Adamts1-KO

Strain Name：C57BL/6Smoc-Adamts1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200624

Adamts1-KO mice (Stock No.NM-KO-200624） carry a knockout allele derived from the targeted deletion of exon 5-7. While Adamts1-KO(2) mice (Stock No.NM-KO-2115470）mice carrying the exon 2 deletion.

Mice

Apc-L850X

Strain Name：C57BL/6Smoc-Apcem1(L850X)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200001

Familial adenomatous polyposis (FAP) is a heritable condition in which affected individuals develop benign intestinal polyps. Often, polyps progress to colorectal carcinomas later in life. The mutation of C57BL/6-Apcem1(L850X)Smoc(NM-KI-200001) strain of SMOC refers to the ApcMin model (Jax: 002020 ), a useful model to study intestinal adenomas. The C57BL/6-Apcem1(L850X)Smoc strain is highly susceptible to spontaneous intestinal adenoma formation and can be used as a research model for human FAP. These mice carry a p.L850X mutation of Apc gene.

Mice

Apc-Flox

Strain Name：C57BL/6Smoc-Apctm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200013

These mice carry loxP sites flanking exon 15 of Apc gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Apc gene.

Mice

Palld-KO

Strain Name：B6;129S-Palldtm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00009

Palld gene knockout strain.

Mice

Cdkn2a-Flox(p19-Flox)

Strain Name：C57BL/6Smoc-Cdkn2aem2(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200151

These mice carry loxP sites flanking exon 1 of Cdkn2a-p19ARF transcript.

Mice

Atr-Flox

Strain Name：C57BL/6Smoc-Atrem1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200081

These mice carry loxP sites flanking exon 43-44 of Atr gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Atr gene.

Mice

Tmprss2-KO

Strain Name：C57BL/6Smoc-Tmprss2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200647

Exon 3 of Tmprss2 gene was deleted to generate Tmprss2 knockout mice.

Mice

Tgfbr2-Flox(2)

Strain Name：C57BL/6Smoc-Tgfbr2em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200228

These mice carry loxP sites flanking exon 4 of Tgfbr2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Tgfbr2 gene.While Tgfbr2-Flox(Stock No.NM-CKO-200026）mice carrying the loxP sites flanking exon 3 of Tgfbr2 gene.

Mice

Foxo1-Flox

Strain Name：C57BL/6Smoc-Foxo1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200177

These mice carry loxP sites flanking exon 2 of Foxo1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Foxo1 gene.

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