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Mice

Ambra1-Flox

Strain Name:C57BL/6Smoc-Ambra1em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200059

These mice carry loxP sites flanking exon4 of Ambra1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ambra1 gene.

Mice

hPD-L1

Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00062

The endogenous mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene . While hPD-L1(2)(Stock No.NM-HU-190039) mice function similarly to hPD-L1 mice,for more detailed information please contact our technical advisor.

Mice

h4-1BB(2)

Strain Name:C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190077

The endogenous mouse Tnfrsf9 gene was replaced by human TNFRSF9(4-1BB) gene. While h4-1BB mice(Stock No.NM-HU-00099)have been pulled from shelves for some reasons.

Mice

h4-1BBL

Strain Name:C57BL/6Smoc-Tnfsf9em1(hTNFSF9)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00048

The endogenous mouse Tnfsf9 gene was replaced by human TNFSF9 gene.

Mice

H11-CAG-LSL-Myc

Strain Name:C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

R26-CAG-LSL-hWNT1

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-WNT1-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190128

These mice harbor a SA-Frt-2xpA-CAG-Frt-LSL-WNT1-IRES-Luc-2A-tdTomato-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Pfkp-KO

Strain Name:C57BL/6Smoc-Pfkpem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190555

Pde4d-KO mice (Stock No.NM-KO-190555) carry a knockout allele derived from the targeted deletion of exon 4.

Mice

Hif1a-Flox

Strain Name:C57BL/6Smoc-Hif1atm1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-190065

These mice carry loxP sites flanking exon 2 of Hif1a gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Hif1a gene.

Mice

Wrn-KO

Strain Name:C57BL/6Smoc-Wrnem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190902

Exon 5-8 of Wrn gene was deleted to generate Wrn knockout mice.

Mice

Tcf7l2-Flox

Strain Name:C57BL/6Smoc-Tcf7l2em1(flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-200141

These mice carry loxP sites flanking exon 1-3 of Tcf7l2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Tcf7l2 gene.

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