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Models

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Mice

hSIGLEC15

Strain Name：C57BL/6Smoc-Siglec15em1(hSIGLEC15)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190037

The endogenous mouse Siglec15 gene was replaced by human SIGLEC15 gene.

Mice

hPD-L2(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1lg2em1(hPDCD1LG2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190061

The endogenous mouse Pdcd1lg2 gene was replaced by human PDCD1LG2 gene.

Mice

hPD-L1/hCTLA-4

Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4)Cd274em1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00102

hPD-L1(NM-HU-00062) was crossed with hCTLA4(NM-HU-00014)to generate hPD-1/hCTLA4 mice

Mice

hPD-L1/hSEMA4D

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Sema4dem1(hSemA4D)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190034

hPD-L1(NM-HU-00062) was crossed with hSEMA4D(NM-HU-00117) to generate hPD-L1/hSEMA4D.

Mice

hPSGL-1

Strain Name：C57BL/6Smoc-Selplgem1(hSELPLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00046

The endogenous mouse Selplg gene was replaced by human SELPLG gene.

Mice

hPD-1/hSTING

Strain Name：C57BL/6Smoc-Tmem173tm1(hTMem173)Pdcd1em1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000104

hPD-1(NM-HU-00015) was crossed with hSTING(NM-HU-190036) to generate hPD-1/hSTING.

Mice

hPD-L1/hTIM3

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Havcr2em1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190056

hPD-L1(NM-HU-00062) was crossed with hTIM3(NM-HU-00054) to generate hPD-L1/hTIM3.

Mice

hCD73(2)

Strain Name：C57BL/6Smoc-Nt5etm3(NT5E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200009

The endogenous mouse Nt5e gene was replaced by human NT5E gene.

Mice

hTLR2

Strain Name：C57BL/6Smoc-Tlr2em2(hTLR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190066

The endogenous mouse Tlr2 gene was replaced by human TLR2 gene.

Mice

hPD-1/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Havcr2em1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00103

hPD-1(NM-HU-00015) was crossed with hTIM3(NM-HU-00054)to generate hPD-1/hTIM3 mice

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