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Models

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Mice

hSEMA4D

Strain Name：C57BL/6Smoc-Sema4dem1(hSEMA4D)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00117

The endogenous mouse Sema4d gene was replaced by human SEMA4D gene.

Mice

hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00100

hPD-1(NM-HU-00015) was crossed with hPD-L1(NM-HU-00062)to generate hPD-1/hPD-L1 mice

Mice

hPD-L1/hTIGIT

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Tigitem1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18013

hPD-L1(NM-HU-00062) was crossed with hTIGIT(NM-HU-00053) to generate hPD-L1/hTIGIT.

Mice

hCD20

Strain Name：C57BL/6Smoc-Ms4a1em2(hCD20)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190068

The endogenous mouse Cd20(Ms4a1) gene was replaced by human CD20 gene. While hCD20(2)(Stock No.NM-HU-200114) mice function similarly to hCD20 mice,for more detailed information please contact our technical advisor.

Mice

hCSF2

Strain Name：C57BL/6Smoc-Csf2tm1(CSF2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190046

The endogenous mouse Csf2 gene was replaced by human CSF2 gene.

Mice

hIL6R

Strain Name：C57BL/6Smoc-Il6raem1(hIL6R)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00044

The endogenous mouse Il6ra gene was replaced by human IL-6R gene .

Mice

hTLR7

Strain Name：C57BL/6Smoc-Tlr7tm1(hTLR7)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-18027

The endogenous mouse Tlr7 gene was replaced by humanTLR7 gene.

Mice

hCCR8

Strain Name：C57BL/6Smoc-Ccr8em1(hCCR8) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190053

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene. While hCCR8(2)(Stock No.NM-HU-2000054) mice function similarly to hCCR8 mice,for more detailed information please contact our technical advisor.

Mice

hIL17A

Strain Name：C57BL/6Smoc-Il17atm1(hIL17A)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00042

The endogenous mouse Il17a gene was replaced by human IL17A gene.

Mice

hTIM3

Strain Name：C57BL/6Smoc-Havcr2em1(hHAVCR2)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00054

The endogenous mouse Tim3 gene was replaced by human TIM3 gene .

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