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Models

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Mice

Foxn1-IRES-Cre

Strain Name：C57BL/6Smoc-Foxn1em1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200106

A IRES-iCre expression cassette was knocked into the Foxn1 gene stop codon site. The protein encoded by Foxn1 (forkhead box N1) gene is part of the forkhead family or transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. When crossed with a strain carrying a gene flanked by sites, the flanked gene will be removed in thymic epithelial cell and keratinocytes.

Mice

BALB/c

Strain Name：BALB/cAnSmoc
Strain State：Repository Live | Cat. NO.：SM-003

BALB/c is one of the most widely used inbred lines in biomedical research, especially in immunology and infectious disease research. The incidence of breast tumors is about 10% to 20%. There is a certain number of ovarian, adrenal, pulmonary tumors, and leukemia that occurs. Lung cancer occurs in 26% of female mice and 29% of male mice. The incidence of leukemia is 12% in females and 10% in males. Blood pressure was the highest compared to other inbred mice and had spontaneous hypertension.

Mice

Eif4b-KO

Strain Name：C57BL/6Smoc-Eif4Bem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191114

Exon 3-4 of Eif4b gene was deleted to generate Eif4b knockout mice.

Mice

Cab39l-KO

Strain Name：C57BL/6Smoc-Cab39Lem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191104

Exon 5-6 of Cab39l gene was deleted to generate Cab39l knockout mice.

Mice

Btg2-KO

Strain Name：C57BL/6Smoc-Btg2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200587

Exon 2 of Btg2 gene was deleted to generate Btg2 knockout mice.

Mice

Mmp7-KO

Strain Name：C57BL/6Smoc-Mmp7em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190699

Exon 4-6 of Mmp7 gene was deleted to generate Mmp7 knockout mice.

Mice

Sfrp1-KO

Strain Name：C57BL/6Smoc-Sfrp1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190685

Exon 1 of Sfrp1 gene was deleted to generate Sfrp1 knockout mice.

Mice

Ptpn2-Flox

Strain Name：C57BL/6Smoc-Ptpn2em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200049

These mice carry loxP sites flanking exon 3 of Ptpn2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Ptpn2 gene.

Mice

Reg3b-KO

Strain Name：C57BL/6Smoc-Reg3bem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200709

Reg3b-KO mice (Stock No.NM-KO-200709） carry a knockout allele derived from the targeted deletion of exon 3-4. While Reg3b-KO(2) mice (Stock No.NM-KO-200791）carrying the exon 2-6 deletion.

Mice

Tgfb2-KO

Strain Name：C57BL/6Smoc-Tgfb2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190548

Exon 4 of Tgfb2 gene was deleted to generate Tgfb2 knockout mice.

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