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Models

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Mice

hPD-L1/hOX40

Strain Name:C57BL/6Smoc-Cd274em1(hPD-L1)Tnfrsf4em1(hTNFRSF4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00111

hPD-L1(NM-HU-00062)was crossed with hOX40(NM-HU-00041)to generate hPD-L1/hOX40.

Mice

hPD-1/hOX40

Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Tnfrsf4em3(hTNFRSF4) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00108

hPD-1(NM-HU-00015)was crossed with hOX40(NM-HU-00041)to generate hPD-1/hOX40.

Mice

hOX40(2)

Strain Name:C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00078

The exon1-5 and partial exon6 of endogenous mouse Tnfrsf4(Ox40) gene was replaced by the corresponding region of human TNFRSF4(OX40) gene. While hOX40(Stock No.NM-HU-00041) mice function similarly to hOX40(2) mice,for more detailed information please contact our technical advisor.

Mice

hPD-1/hPD-L1/hIDO1

Strain Name:C57BL/6Smoc-Ido1tm1(hIDO1)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-00120

hPD-1(NM-HU-00015),hPD-L1(NM-HU-00062) were crossed with hIDO1(NM-HU-00061) to generate hPD-1/hPD-L1/hIDO1.

Mice

R26-CAG-hFcRn

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00081

A human FCGRT expression cassette was knocked in mouse Rosa26 loci.

Mice

NVG-hIL15

Strain Name:NOD.Cg-PrkdcscidIl2rgem1SmocIl15em1(hIL15)Smoc
Strain State:Repository Live | Cat. NO.:GM-NVG-210001

The endogenous mice Il15 gene was replaced by human IL15 gene.

Mice

hFCGRT(NMG)

Strain Name:NOD-PrkdcscidIl2rgem1Fcgrtem2(FCGRT)Smoc
Strain State:Repository Live | Cat. NO.:NM-NSG-020

The background of this strain is NMG, and its endogenous Fcgrt gene is replaced with human FCGRT.

Mice

hHGF(NMG)

Strain Name:NOD-PrkdcscidIl2rgem1Hgfem1(hHGF)Smoc
Strain State:Developing | Cat. NO.:NM-NSG-013

The endogenous mouse Hgf gene was replaced by human HGF gene. (NMG Background)

Mice

Rag2/IL2rg-KO/hCD40

Strain Name:C57BL/6Smoc-Cd40em1(hCD40)Rag2em1Il2rgem1/Smoc
Strain State:Developing | Cat. NO.:NM-HU-2000112

The Rag2 and Il2rg genes of the CD40 humanized mouse were deleted.

Mice

hCCR2

Strain Name:C57BL/6Smoc-Ccr2em2(hCCR2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18026

The endogenous mouse Ccr2 gene was replaced by human CCR2 gene.

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