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Mice

hCTLA-4(2)

Strain Name：C57BL/6Smoc-Ctla4em2(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190038

Extracellular domain of mouse Ctla4 gene was replaced by human CTLA4 gene. While hCTLA4(Stock No.NM-HU-00014) mice function similarly to hCTLA4(2) mice,for more detailed information please contact our technical advisor.

Mice

hOX40L(2)

Strain Name：C57BL/6Smoc-Tnfsf4em2(TNFSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200005

The endogenous mouse Tnfsf4 gene was replaced by human TNFSF4 gene . While hOX40L(Stock No.NM-HU-00070) mice function similarly to hOX40L(2) mice,for more detailed information please contact our technical advisor.

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1

Strain Name：C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Pdcd1em1(hPDCD1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-220068

The Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1 mouse model was obtained by deleting all sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hPD-1(NM-HU-00015) mouse.

Mice

hIL5/hIL5R(2)

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Il5raem2(hIL5RA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220010

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(3)(Stock No.NM-HU-220011) function similarly to hIL5/hIL5R(2) mice, for more detailed information please contact our technical advisor.

Mice

hFCRN(2)

Strain Name：C57BL/6Smoc-Fcgrtem2(hFCGRT)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190070

The endogenous mouse Fcgrt gene was replaced by human FCGRT gene.While hFCRN(Stock No.NM-HU-00109) and hFCRN(3)(Stock No.NM-HU-2000032）mice function similarly to hFCRN(2) mice,for more detailed information please contact our technical advisor.

Mice

hIL5/hIL5R(3)

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Il5raem3(hIL5RA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220011

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.

Mice

hSIRPA(2)/hCD47/hPD-L1

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274em1(hCD274)Cd47em1(hCD47)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000095

hPD-L1(NM-HU-00062),hCD47(NM-HU-00050) was crossed with hSIRPA(2) (NM-HU-18015) to generate hSIRPA(2)/hCD47/hPD-L1.

Mice

hPD-1/hSIGLEC15

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Siglec15em1(hSIGLEC15)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000093

hPD-1(NM-HU-00015) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-1/hSIGLEC15.

Mice

Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA-4

Strain Name：C57BL/6Smoc-Fcgr2bem1Fcgr3em1Fcgr4em1Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-220070

The Fcgr2b-Fcgr3-Fcgr4-KO/hPD-1/hCTLA4 mouse model was obtained by deleting sequences from upstream of Fcgr3 gene to the 3'UTR of Fcgr2b gene in the hPD-1/hCTLA4(NM-HU-00079) mouse.

Mice

hPD-L1/hSIRPA(2)

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274em1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000099

hPD-L1(NM-HU-00062) was crossed with hSIRPA(2)(NM-HU-18015) to generate hPD-L1/hSIRPA(2).

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