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Models

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Mice

hPD-1/hSEMA4D

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Sema4dtm1(hSemA4D)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190033

hPD-1(NM-HU-00015) was crossed with hSEMA4D(NM-HU-00117) to generate hPD-1/hSEMA4D.

Mice

hPD-1/hVISTA

Strain Name:C57BL/6Smoc-Visrtm1(hVSIR)Pdcd1tm1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000092

hPD-1(NM-HU-00015) was crossed with hSIRPA(2) (NM-HU-18015) to generate hPD-1/hVISTA.

Mice

hPD-1/hCD3E

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd3etm1(hCD3E)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18021

hPD-1(NM-HU-00015)was crossed with hCD3E(NM-HU-00114)to generate hPD-1/hCD3E。

Mice

hCTLA-4(2)

Strain Name:C57BL/6Smoc-Ctla4tm2(hCTLA4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190038

Extracellular domain of mouse Ctla4 gene was replaced by human CTLA4 gene. While hCTLA4(Stock No.NM-HU-00014) mice function similarly to hCTLA4(2) mice,for more detailed information please contact our technical advisor.

Mice

hHGF(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1Hgfem1(hHGF)Smoc
Strain State:Developing | Cat. NO.:NM-NSG-013

The endogenous mouse Hgf gene was replaced by human HGF gene. (NMG Background)

Mice

hOX40L(2)

Strain Name:C57BL/6Smoc-Tnfsf4tm2(TNFSF4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200005

The endogenous mouse Tnfsf4 gene was replaced by human TNFSF4 gene . While hOX40L(Stock No.NM-HU-00070) mice function similarly to hOX40L(2) mice,for more detailed information please contact our technical advisor.

Mice

hIL13

Strain Name:C57BL/6Smoc-Il13tm2(hIL13)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190069
Validation Data:Presence

The endogenous mouse Il13 gene was replaced by human IL13 gene.

Mice

hICOS(2)

Strain Name:C57BL/6Smoc-Icostm2(hICOS)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190030
Validation Data:Presence

The endogenous mouse Icos gene was replaced by human ICOS gene. While hICOS(Stock No.NM-HU-00052) mice function similarly to hICOS(2) mice,for more detailed information please contact our technical advisor.

Mice

hPD-1/hCD28

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd28tm2(hCD28)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000097

hPD-1(NM-HU-00015) was crossed with hCD28(NM-HU-190011) to generate hPD-1/hCD28.

Mice

hIL5/hIL5R(2)

Strain Name:C57BL/6Smoc-Il5tm3(hIL5)Il5ratm2(hIL5RA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-220010
Validation Data:Presence

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(3)(Stock No.NM-HU-220011) function similarly to hIL5/hIL5R(2) mice, for more detailed information please contact our technical advisor.

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