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Models

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Mice

hPD-1/hTIGIT

Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1) Tigittm1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00104

hPD-1(NM-HU-00015) was crossed with hTIGIT(NM-HU-00053) to generate hPD-1/hTIGIT.

Mice

hIL4/hIL4R

Strain Name:C57BL/6Smoc-Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000106
Validation Data:Presence

These mice are obtained through breeding of two single gene humanized mice.

Mice

hSIGLEC15(BALB/c)

Strain Name:BALB/cAnSmoc-Siglec15tm2(hSIGLEC15) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200001
Validation Data:Presence

The endogenous mouse Siglec15 gene was replaced by human SIGLEC15 gene .

Mice

hPD-L1/hVISTA

Strain Name:C57BL/6Smoc-Visrtm1(hVSIR)Cd274tm1(hCD274)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000094

hPD-L1(NM-HU-00062) was crossed with hVISTA(NM-HU-00118) to generate hPD-L1/hVISTA.

Mice

hPD-L2(BALB/c)

Strain Name:BALB/cAnSmoc-Pdcd1lg2tm1(hPDCD1LG2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190061

The endogenous mouse Pdcd1lg2 gene was replaced by human PDCD1LG2 gene.

Mice

hPD-L1/hVEGFR2

Strain Name:C57BL/6Smoc-Cd274tm1(hCD274)Kdrtm2(hKDR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000102

hPD-L1(NM-HU-00062) was crossed with hKDR(NM-HU-00098) to generate hPD-L1/hKDR.

Mice

hPD-L1(E3-4)

Strain Name:C57BL/6Smoc-Cd274tm2(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190039
Validation Data:Presence

Extracellular domain of mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene. While hPD-L1(Stock No.NM-HU-00062) mice function similarly to hPD-L1(2) mice,for more detailed information please contact our technical advisor.

Mice

hOX40L

Strain Name:C57BL/6Smoc-Tnfsf4tm1(hTNFSF4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00070

The endogenous mouse Tnfsf gene was replaced by human TNFSF4(OX-40L) gene . While hOX40L(2)(Stock No.NM-HU-200005) mice function similarly to hOX40L mice,for more detailed information please contact our technical advisor.

Mice

hPD-L1/hCD40

Strain Name:C57BL/6Smoc-Cd274tm1(hPD-L1)Cd40tm1(hCD40)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18024

hPD-L1(NM-HU-00062) was crossed with hCD40(NM-HU-00076) to generate hPD-L1/hCD40.

Mice

hIL1B

Strain Name:C57BL/6Smoc-Il1btm3(hIL1B)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190047
Validation Data:Presence

The endogenous mouse Il1b gene was replaced by human IL1B gene.

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