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Research on Diseases

genetics diseases studies diseases research diseases

Shanghai Model Organisms provides a professional R&D platform for genetically-engineered mouse, zebrafish and nematode models, a service platform for phenotyping, and a rich repository of disease mouse models to support your studies on disease genetics, pathogenesis, drug treatments, and more.

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About Us

Our vision is to become the leader in the field of genetically modified animal models，helping people understand the life science and improving quality of life around the world.

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Smad4 CKO Mouse Model

Our own-developed Smad4 conditional knockout mice (Smad4-CKO) can be used to study cell proliferation and tumor suppression.

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Pten CKO Mouse Model

Our own-developed mouse model of Pten conditional knockout (Pten-CKO) can be mated with mice carrying tissue-specific Cre expression to obtain mice with homozygous deletion of Pten in specific tissues or cells, thus avoiding the embryonic death caused by systemic and homozygous Pten knockout. Pten-CKO mice can be used to study tumorigenesis, anti-tumor targets, neurogenesis, glial differentiation and cerebellar development.

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Brca1 CKO Mouse Model

Our own-developed Brca1 conditional knockout mice (Brca1-CKO) can be used to study breast cancer.

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Rb1 CKO Mouse Model

With the ability to avoid the risk of death caused by homozygous and systemic knockout, our own-developed Rb1 conditional knockout mice (Rb1-CKO) can be used to study cancer, cell cycle or aging.

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