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Models

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Mice

hPD-L1/hSIRPA(2)

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd274em1(hCD274)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000099

hPD-L1(NM-HU-00062) was crossed with hSIRPA(2)(NM-HU-18015) to generate hPD-L1/hSIRPA(2).

Mice

hIL4

Strain Name：C57BL/6Smoc-Il4tm3(hIL4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190071

The endogenous mouse Il4 gene was completely or partially replaced by human IL4 gene via ESC targeting.

Mice

hPD-1/hCD27(2)

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd27tm2(hCD27)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000096

hPD-1(NM-HU-00015) was crossed with hCD27(2)(NM-HU-190035) to generate hPD-1/hCD27(2).

Mice

hIL6

Strain Name：C57BL/6Smoc-Il6tm1(hIL6)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18017

This IL6 humanized mouse model was established by replacing the mouse Il6 gene coding exon1-5 and introns with the human IL6 corresponding sequence by homologous recombination via ES cell targeting.

Mice

hPD-1

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00015

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

Mice

hPD-L1

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00062

The endogenous mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene . While hPD-L1(2)(Stock No.NM-HU-190039) mice function similarly to hPD-L1 mice,for more detailed information please contact our technical advisor.

Mice

h4-1BB(2)

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190077

The endogenous mouse Tnfrsf9 gene was replaced by human TNFRSF9(4-1BB) gene. While h4-1BB mice(Stock No.NM-HU-00099）have been pulled from shelves for some reasons.

Mice

h4-1BBL

Strain Name：C57BL/6Smoc-Tnfsf9em1(hTNFSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00048

The endogenous mouse Tnfsf9 gene was replaced by human TNFSF9 gene.

Mice

huHSC-(NMG)

Strain Name：huHSC-(NMG)
Strain State：Repository Live | Cat. NO.：NM-NSG-017

After irradiation, NMG mice are injected with CD34+ hematopoietic stem cells (CD34+ HSC).

Mice

Palld-KO

Strain Name：B6;129S-Palldtm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00009

Palld gene knockout strain.

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