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Mice

H11-CAG-LSL-Myc

Strain Name:C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

R26-CAG-LSL-hWNT1

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpA-CAG-FRT-loxp-STOP-loxp-WNT1-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190128

These mice harbor a SA-Frt-2xpA-CAG-Frt-LSL-WNT1-IRES-Luc-2A-tdTomato-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Pdk1-KO

Strain Name:C57BL/6Smoc-Pdk1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-191074

Exon 2 of Pdk1 gene was deleted to generate Pdk1 knockout mice.

Mice

Pfkp-KO

Strain Name:C57BL/6Smoc-Pfkpem1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190555

Pde4d-KO mice (Stock No.NM-KO-190555) carry a knockout allele derived from the targeted deletion of exon 4.

Mice

Chrna5-KO

Strain Name:C57BL/6Smoc-Chrna5em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190568

Exon 5 of Chrna5 gene was deleted to generate Chrna5 knockout mice.

Mice

Rps6ka1-KO

Strain Name:C57BL/6Smoc-Rps6Ka1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-191097

Exon 4 of Rps6ka1 gene was deleted to generate Rps6ka1 knockout mice.

Mice

Rps6kb2-KO

Strain Name:C57BL/6Smoc-Rps6Kb2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-191118

Exon 2-5 of Rps6kb2 gene was deleted to generate Rps6kb2 knockout mice.

Mice

Hif1a-Flox

Strain Name:C57BL/6Smoc-Hif1atm1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-190065

These mice carry loxP sites flanking exon 2 of Hif1a gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Hif1a gene.

Mice

Casp7-KO

Strain Name:C57BL/6Smoc-Casp7em1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KO-190929

Exon 3-5 of Casp7 gene was deleted to generate Casp7 knockout mice.

Mice

Sympk-KO

Strain Name:C57BL/6Smoc-Sympkem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-191041

Exon 6 of Sympk gene was deleted to generate Sympk knockout mice.

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