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Mice

hSIRPA(2)/hCD47

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000111

This SIRPA and CD47 double Knock-in strain is established by crossing hSIRPA and hCD47 mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.While hSIRPA/hCD47 (Stock No.NM-HU-190019) have been pulled from shelves for some reasons.

Mice

hPD-1/hSEMA4D

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Sema4dem1(hSemA4D)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190033

hPD-1(NM-HU-00015) was crossed with hSEMA4D(NM-HU-00117) to generate hPD-1/hSEMA4D.

Mice

hPD-1/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Havcr2em1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00103

hPD-1(NM-HU-00015) was crossed with hTIM3(NM-HU-00054)to generate hPD-1/hTIM3 mice

Mice

hHGF(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Hgfem1(hHGF)Smoc
Strain State：Developing | Cat. NO.：NM-NSG-013

The endogenous mouse Hgf gene was replaced by human HGF gene. (NMG Background)

Mice

hPSGL-1

Strain Name：C57BL/6Smoc-Selplgem1(hSELPLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00046

The endogenous mouse Selplg gene was replaced by human SELPLG gene.

Mice

hPD-1(BALB/c)

Strain Name：BALB/cAnSmoc-Pdcd1em1(hPDCD1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190079

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

Mice

hIL13

Strain Name：C57BL/6Smoc-Il13em2(hIL13)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190069

The endogenous mouse Il13 gene was replaced by human IL13 gene.

Mice

hPD-L1/hSIGLEC15

Strain Name：C57BL/6Smoc-Cd274em1(hCD274)Siglec15em1(hSIGLEC15)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000103

hPD-L1(NM-HU-00062) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-L1/hSIGLEC15.

Mice

hIDO1

Strain Name：B6;129S-Ido1tm1(hIDO1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00061

The endogenous mouse Ido1 gene was replaced by human IDO1 gene.

Mice

hICOS

Strain Name：C57BL/6Smoc-Icosem1(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00052

The endogenous mouse Icos gene was replaced by human ICOS gene. While hICOS(2)(Stock No.NM-HU-190030) mice function similarly to hICOS mice,for more detailed information please contact our technical advisor.

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