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Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome

Model Organisms：小鼠 Product & Service：PRKAG2 H530R Research field：Heart

室性心律失常 AAV9 基因治疗

In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9- activator...

Model Organisms：小鼠 Product & Service：- Research field：Gene regulation

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

CRISPR-Cas9 technology Broad Institute genetically modified mouse

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

F0 homozygous mice gene knockout Crispr/Cas projects immediate phenotype analysis research efficiency cost optimization.

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

SMOC Launched U-HuDTMbase®, Inclusive Resource Library of Innovative Therapeutic Target-Humanized Mouse Models, to Accelerate Novel Drug Discovery

U-HuDTMbase® is composed of more than 600 therapeutic target-humanized mouse models, including multiple background strains, and has covered almost all commonly studied areas, such as oncology, metabolism, immunity, inflammation and more.

Genotyping method for CRISPR/Cas9 Knockout mouse

Genotyping method for CRISPR/Cas9 point mutation mouse

How do I design primers for genotyping of conventional knockout mice?

conventional knockout mice primer design genotyping protocol

Overview of gene editing technology

gene editing crispr gene editing gene editing technology

Popular Model Organisms

genetically modified organisms transgenic organisms genetically modified organisms examples

Model organisms are instrumental to the study of gene functions. Gene editing technology has always played a crucial role in the research on gene functions, diseases and drug discovery, through its application in genetic engineering of model organisms, mimicking of human diseases, as well as observation of physiological or pathological changes. In particular, the CRISPR/Cas9 technology has achieved remarkable breakthroughs in recent years, significantly improving the efficiency of genetic engineering in model organisms, and facilitating more extensive and in-depth applications of animal models in various research fields.