Strain Name:C57BL/6Smoc-Crhr1em1(N-EGFP, flox)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-CKO-2100082
These mice carry loxP sites flanking exon 2 of Crhr1 gene. The EGFP element is inserted into exon 2 of Crhr1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Crhr1 gene. Construction strategy references Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1.