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Mice

hTIGIT

Strain Name：C57BL/6Smoc-Tigittm1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00053
Validation Data：Presence

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(3)(Stock No.NM-HU-200244) mice function similarly to hTIGIT mice,for more detailed information please contact our technical advisor.

Mice

Cav1-KO

Strain Name：C57BL/6Smoc-Cav1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190930

Exon 3 of Cav1 gene was deleted to generate Cav1 knockout mice.

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039
Validation Data：Presence  |  Publications：2piece

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

Itgam-IRES-hCD89/hIGHA1

Strain Name：C57BL/6Smoc-Itgamtm1(IRES-hCD89-WPRE-polyA)sμtm1(hIGHA1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210412
Validation Data：Presence

Itgam-IRES-hCD89(NM-KI-200063) was crossed with hIGHA1(NM-HU-2000086) to generate Itgam-IRES-hCD89/hIGHA1 mice.

Mice

Wt1-CreERT2

Strain Name：C57BL/6Smoc-Wt1em1(CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200127
Validation Data：Presence

A CreERT2-WPRE-pA expression cassette was knocked into the Wt1 gene start codon site.

Mice

Braf-Flox

Strain Name：C57BL/6Smoc-Brafem1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200073

These mice carry loxP sites flanking exon 5 of Braf gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Braf gene.

Mice

hCD40/h4-1BB(2)

Strain Name：C57BL/6Smoc-Cd40tm1(hCD40)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200256
Validation Data：Presence

hCD40(NM-HU-00076)was crossed with h4-1BB(NM-HU-190077) to generate hCD40/h4-1BB(2) mice.

Mice

hB7H4(2)

Strain Name：C57BL/6Smoc-Vtcn1tm2(hVTCN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190075

Extracellular domain of mouse Vtcn1 gene was replaced by human VTCN1 gene. While hB7H4(Stock No.NM-HU-190004) mice function similarly to hB7H4(2) mice,for more detailed information please contact our technical advisor.

Mice

A2ml1-Flox

Strain Name：C57BL/6Smoc-A2ml1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253735

These mice carry loxP sites flanking exon 8-11 of A2ml1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2ml1 gene.

Mice

A2m-Flox

Strain Name：C57BL/6Smoc-A2mem1(flox)Smoc
Strain State：Developing | Cat. NO.：NM-CKO-253744

These mice carry loxP sites flanking exon 2-4 of A2m gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2m gene.

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