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Models

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Mice

hB7H4

Strain Name：C57BL/6Smoc-Vtcn1tm1(hVTCN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190004

This VTCN1 humanized mouse model was established by replacing the mouse Vtcn1 gene with the human VTCN1. While hB7H4(2)(Stock No.NM-HU-190075) mice function similarly to hB7H4 mice,for more detailed information please contact our technical advisor.

Mice

hB7H3/hPD-1

Strain Name：C57BL/6Smoc-Cd276tm2(hCD276)Pdcd1tm1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210349

hB7-H3(NM-HU-00107) was crossed with hPD-1(NM-HU-00015) to generate hB7H3/hPD-1 mice.

Mice

hBTLA(2)

Strain Name：C57BL/6Smoc-Btlatm2(hBTLA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190040
Validation Data：Presence

Extracellular domain of mouse Btla gene was replaced by human BTLA gene. While hBTLA mice(Stock No.NM-HU-18014）have been pulled from shelves for some reasons.

Mice

hCD20(2)

Strain Name：C57BL/6Smoc-Ms4a1tm3(hCD20)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200114
Validation Data：Presence

Extracellular and transmembrane region of the endogenous mouse Ms4a1 gene was replaced by corresponding region of human CD20 gene. While hCD20(Stock No.NM-HU-190068) mice function similarly to hCD20(2) mice,for more detailed information please contact our technical advisor.

Mice

hCD3E

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00114
Validation Data：Presence

The endogenous mouse Cd3e gene was replaced by human CD3E gene . While hCD3E(2)(Stock No.NM-HU-210023) mice function similarly to hCD3E mice,for more detailed information please contact our technical advisor.

Mice

Tmem119-2A-CreERT2

Strain Name：C57BL/6Smoc-Tmem119em2(P2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200234
Validation Data：Presence  |  Publications：2piece

A P2A-CreERT2 expression cassette was knocked into the Tmem119 gene stop codon site.

Mice

HLA-A2.22/B2M

Strain Name：C57BL/6Smoc-H2-D1tm1(hB2M/HLA-A2)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210010

The endogenous mice H2-D1 gene was replaced by human B2M/HLA-A2 gene

Mice

hCD27(2)

Strain Name：C57BL/6Smoc-Cd27tm3(hCD27)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190035
Validation Data：Presence

The endogenous mouse Cd27 gene was replaced by human CD27 gene. While hCD27 mice(Stock No.NM-HU-00093）have been pulled from shelves for some reasons.

Mice

Apc-Flox

Strain Name：C57BL/6Smoc-Apctm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200013

These mice carry loxP sites flanking exon 15 of Apc gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Apc gene.

Mice

hOX40

Strain Name：C57BL/6Smoc-Tnfrsf4tm1(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00041
Validation Data：Presence

The endogenous mouse Tnfrsf4(Ox40) gene was replaced by human TNFRSF4(OX40) gene. While hOX40(2)(Stock No.NM-HU-00078) mice function similarly to hOX40 mice,for more detailed information please contact our technical advisor.

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