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Models

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Mice

hCCR8(2)

Strain Name：C57BL/6Smoc-Ccr8tm3(hCCR8)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000054
Validation Data：Presence

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene. While hCCR8(Stock No.NM-HU-190053) mice function similarly to hCCR8(2) mice,for more detailed information please contact our technical advisor.

Mice

hCCL4

Strain Name：C57BL/6Smoc-Ccl4tm1(hCCL4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210013
Validation Data：Presence

The endogenous mice Ccl4 gene was replaced by human CCL4 gene

Mice

h4-1BB(2)/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210357

h4-1BB(2)(NM-HU-190077), hPD-L1(NM-HU-00062) and hPD-1(NM-HU-00015) was crossed together to generate h4-1BB(2)/hPD-1/hPD-L1 mice.

Mice

hAQP4

Strain Name：C57BL/6Smoc-Aqp4tm1(hAQP4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210001

The endogenous mice Aqp4 gene was replaced by human AQP4 gene

Mice

hC1QA

Strain Name：C57BL/6Smoc-C1qatm1(hC1QA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-200282

The endogenous mice C1qa gene was replaced by human C1QA gene.

Mice

hBCMA

Strain Name：C57BL/6Smoc-Tnfrsf17tm1(hBCMA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200228
Validation Data：Presence

The endogenous mice Bcma gene was replaced by human BCMA gene.

Mice

hC5AR1

Strain Name：C57BL/6Smoc-C5ar1tm1(hC5AR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204989
Validation Data：Presence

The endogenous mice C5ar1 gene was replaced by human C5AR1 gene.

Mice

hPD-1/Cd8a-IRES-Akaluc-2A-EGFP

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd8atm1(V5-IRES-Akaluc-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210373

hPD-1(NM-HU-00015) was crossed with Cd8a-IRES-Luc-2A-EGFP(NM-KI-18030) to generate hPD-1/Cd8a-IRES-Luc-2A-EGFP mice

Mice

hCD38(2)

Strain Name：C57BL/6Smoc-Cd38tm2(CD38)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190059
Validation Data：Presence

The endogenous mouse Cd38 gene was replaced by human CD38 gene. While hCD38 mice(Stock No.NM-HU-00113）have been pulled from shelves for some reasons.

Mice

Rag2-KO

Strain Name：C57BL/6Smoc-Rag2em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190429
Validation Data：Presence  |  Publications：2piece

Partial exon 3 of Rag2 gene was deleted to generate Rag2 knockout mice. Deletion of this region will cause frameshift and result in loss of function of mouse Rag2 gene.

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