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Models

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Mice

R26-CAG-2xKRAB-dCas9-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-Loxp-2xKRAB-dCas9-IRES-EGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18007
Validation Data：Presence

These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted.

Mice

hCD3EDG/hTPBG

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tpbgtm1(hTPBG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220111

hCD3EDG(NM-HU-220120) mice were crossed with hTPBG(NM-HU-200239) mice to generate hCD3EDG/hTPBG mice

Mice

Abcc2-KO

Strain Name：C57BL/6Smoc-Abcc2em3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18017

Exon4-6 of Abcc2 gene were deleted to generate Abcc2 knockout mice.

Mice

hCD3EDG/hCD40/h4-1BB(2)

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd40tm1(hCD40)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220117

hCD3EDG/hCD40(NM-HU-220116) mice were crossed with hCD3EDG/h4-1BB(2)(NM-HU-220110) to generate hCD3EDG/hCD40/h4-1BB(2) mice.

Mice

Hif1a-Flox

Strain Name：C57BL/6Smoc-Hif1atm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-190065
Publications：1piece

These mice carry loxP sites flanking exon 2 of Hif1a gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Hif1a gene.

Mice

hCD3EDG/h4-1BB(2)

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220110

hCD3EDG(NM-HU-220120) mice were crossed with h4-1BB(2)(NM-HU-190077) to generate hCD3EDG/h4-1BB(2) mice.

Mice

hTIGIT/hPVR

Strain Name：C57BL/6Smoc-Tigittm1(hTIGIT)Pvrtm1(hPVR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000091
Validation Data：Presence

These mice are obtained through breeding of hTIGIT(NM-HU-00053) and hPVR(NM-HU-190012) mice.

Mice

Acadl-KO

Strain Name：C57BL/6Smoc-Acadlem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201235

Exon 5 of Acadl gene was deleted to generate Acadl knockout mice.

Mice

hIL2RB/hPD-1

Strain Name：C57BL/6Smoc-Il2rbtm1(hIL2RB)Pdcd1tm1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220036

hIL2RB(NM-HU-2000055) mice were crossed with hPD-1(NM-HU-00015) to generate hIL2RB/hPD-1 mice.

Mice

R26-CAG-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-Luc-EGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00087
Validation Data：Presence

This R26-(CAG-Luc-EGFP) strain was generated by crossing R26-(CAG-LSL-Luc-EGFP)(NM-KI-190095) mice with Ddx4-Cre mice.

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