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Mice

hGEM

Strain Name：C57BL/6Smoc-Gemtm1(hGem)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200249

The endogenous mice Gem gene was replaced by human GEM gene.

Mice

R26-CAG-LSL-hIDH2*R140Q-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190075

These mice harbor a CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

Aadacl2-Flox

Strain Name：C57BL/6Smoc-Aadacl2em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253928

These mice carry loxP sites flanking exon 2 of Aadacl2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl2 gene.

Mice

A4gnt-KO

Strain Name：C57BL/6Smoc-A4gntem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201369

Exon 2-3 of A4gnt gene was deleted to generate A4gnt knockout mice.

Mice

Dbt-KO

Strain Name：C57BL/6Smoc-Dbtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200633

Exon 2 of Dbt gene was deleted to generate Dbt knockout mice.

Mice

hIL5/hIL5R(3)

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Il5ratm3(hIL5RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220011
Validation Data：Presence

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.

Mice

H11-CAG-RSR-tdTomato

Strain Name：C57BL/6Smoc-Igs2em1(CAG-RSR-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18009
Publications：3piece

These mice harbor a CAG-Rox-STOP-Rox-tdTomato conditional expression cassette in mouse H11 locus via homologous recombination.

Mice

hSIRPA(2)/hCD47/hCTLA-4

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Ctla4tm1(hCTLA4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210368

hCTLA4(NM-HU-00014) was crossed with hSIRPA(2)/hCD47(NM-HU-2000111）to generate hSIRPA(2)/hCD47/hCTLA4 mice

Mice

Atp4b-IRES-CreERT2(2)

Strain Name：C57BL/6Smoc-Atp4bem2(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210119
Validation Data：Presence

An IRES-CreERT2 expression cassette was knocked into the Atp4b gene stop codon site. Besides,An IRES-CreERT2-WPRE-pA expression cassette were knock into the Atp4b gene start codon site to generate Atp4b-IRES-CreERT2(Stock No. NM-KI-210118) mice. ATP4B could serve as a tumor suppressor in the tumorigenesis and progression. This strain is useful in studying the function of gastric parietal cells in gastric epithelial homeostasis. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cre-expressing cells after tamoxifen treatment.

Mice

Lmna-c.C1827T

Strain Name：C57BL/6Smoc-Lmnatm1(G609G)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200284
Validation Data：Presence

These mice carry a G609G mutation of Lmna gene.

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