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Models

About 41,228 results
Mice

Dmpk-KO

Strain Name：C57BL/6Smoc-Dmpkem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200635

Exon 1-7 of Dmpk gene was deleted to generate Dmpk knockout mice.

Mice

Tmem173-V154M

Strain Name：C57BL/6Smoc-Tmem173em(V154M)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225039

These mice carry a V154M mutation of Tmem173 gene.

Mice

Notch1-CreERT2

Strain Name：C57BL/6Smoc-Notch1em1(CreERT2-2xpA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200122

A CreERT2-2xpA expression cassette was knocked into the Notch1 gene start codon site. Notch1 performs vital cell functions, such as proliferation, differentiation, apoptosis, and stem cell maintenance. When Notch1-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in NOTCH1 positive cells.

Mice

Park7-KO

Strain Name：C57BL/6Smoc-Park7em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191006

Exon 3-5 of Park7 gene was deleted to generate Park7 knockout mice.

Mice

Ace2-KO

Strain Name：C57BL/6Smoc-Ace2em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190906

exon 3-7 of Ace2 gene was deleted to generate Ace2 knockout mice.

Mice

AA467197-Flox

Strain Name：C57BL/6Smoc-AA467197em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of AA467197 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of AA467197 gene.

Mice

Bckdk-KO

Strain Name：C57BL/6Smoc-Bckdkem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2101591

exon 9-12 of Bckdk gene was deleted to generate Bckdk knockout mice.

Mice

R26-CAG-LSL-hIDH2*R140Q-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190075

These mice harbor a CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

Slc6a11-CreERT2

Strain Name：C57BL/6Smoc-Slc6a11em1(CreERT2-polyA(SV40)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200130

A CreERT2-polyA expression cassette was knocked into the Slc6a11 gene start codon site. Slc6a11 encodes GAT3 (Gabt4), a sodium-dependent transporter that uptakes the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which ends the GABA neurotransmission. When Slc6a11-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLC6A11positive cells. Defects in Slc6a11 may result in epilepsy or behavioral and intellectual defects.

Mice

Myl2-Cre-IRES-EGFP

Strain Name：C57BL/6Smoc-Myl2em1(Cre-IRES-EGFP-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200224

A Cre-IRES-EGFP-WPRE-polyA expression cassette was knocked into the Myl2 gene start codon site.

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