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Models

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Mice

Yme1l1-Flox

Strain Name：C57BL/6Smoc-Yme1l1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253857

These mice carry loxP sites flanking exon 3 of Yme1l1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Yme1l1 gene.

Mice

Slc6a4-KO

Strain Name：C57BL/6Smoc-Slc6a4em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200892

Exon 3-4 of Slc6a4 gene was deleted to generate Slc6a4 knockout mice.

Mice

Car4-DreERT2

Strain Name：C57BL/6Smoc-Car4em1(DreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200193

A DreERT2-Wpre-pA expression cassette was knocked into the Car4 gene start codon site.

Mice

hCD3EDG/hCD38(2)

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd38tm2(hCD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220114

hCD3EDG(NM-HU-220120) mice were crossed with hCD38(2)((NM-HU-190059) to generate hCD3EDG/hCD38 mouse.

Mice

hTIGIT/hCCR8

Strain Name：C57BL/6Smoc-Tigittm1(hTIGIT)Ccr8tm1(hCCR8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210426

hTIGIT(NM-HU-00053) was crossed with hCCR8(NM-HU-190053) to generate hTIGIT/hCCR8 mice.

Mice

hFCGR2B/hOX40

Strain Name：C57BL/6Smoc-Fcgrt2Btm2(hFCGRT2B)Tnfrsf4tm1(hTNFRSF4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200265
Validation Data：Presence

hFCGR2B（NM-HU-2000010） was crossed with hOX40（NM-HU-00041）to generate hFCGR2B/hCD40 mice

Mice

Bag3-Flox

Strain Name：C57BL/6Smoc-Bag3em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-2101856

These mice carry loxP sites flanking exon 4 of Bag3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Bag3 gene.

Mice

Notch1-CreERT2

Strain Name：C57BL/6Smoc-Notch1em1(CreERT2-2xpA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200122
Validation Data：Presence

A CreERT2-2xpA expression cassette was knocked into the Notch1 gene start codon site. Notch1 performs vital cell functions, such as proliferation, differentiation, apoptosis, and stem cell maintenance. When Notch1-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in NOTCH1 positive cells.

Mice

hIL5/hIL5R(2)

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Il5ratm2(hIL5RA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220010
Validation Data：Presence

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(3)(Stock No.NM-HU-220011) function similarly to hIL5/hIL5R(2) mice, for more detailed information please contact our technical advisor.

Mice

Lepr-KO

Strain Name：C57BL/6Smoc-Leprem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190663

Exon 5 of Lepr gene was deleted to generate Lepr knockout mice.

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