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Models

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Mice

Cdk4-KO

Strain Name：C57BL/6Smoc-Cdk4em1Smoc
Strain State：Developing | Cat. NO.：NM-KO-190614

Exon 3-7 of Cdk4 gene was deleted to generate Cdk4 knockout mice.

Mice

Scgb1a1-IRES-Cre

Strain Name：C57BL/6Smoc-Scgb1a1em1(IRES-Cre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210120

IRES-Cre expression cassette was knocked into the Scgb1a1 gene.

Mice

A4gnt-KO

Strain Name：C57BL/6Smoc-A4gntem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201369

Exon 2-3 of A4gnt gene was deleted to generate A4gnt knockout mice.

Mice

hFOXP2

Strain Name：C57BL/6Smoc-Foxp2em1(hFOXP2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210002

The endogenous mice Foxp2 gene was replaced by human FOXP2 gene

Mice

Lepr-KO

Strain Name：C57BL/6Smoc-Leprem1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190663

Exon 5 of Lepr gene was deleted to generate Lepr knockout mice.

Mice

Ikzf3-KO

Strain Name：C57BL/6Smoc-Ikzf3em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2104251

Exon 8 of Ikzf3 gene was deleted to generate Ikzf3 knockout mice.

Mice

Foxp3-DreERT2

Strain Name：C57BL/6Smoc-Foxp3em5(IRES-DreER)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200198

A IRES-DreER expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

Ptf1a-CreERT2

Strain Name：C57BL/6Smoc-Ptf1aem1(CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200118

A CreERT2-WPRE-pA expression cassette was knocked into the Ptf1a gene start codon site.

Mice

Atp4b-IRES-CreERT2(2)

Strain Name：C57BL/6Smoc-Atp4bem2(IRES-CreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210119

An IRES-CreERT2 expression cassette was knocked into the Atp4b gene stop codon site. Besides,An IRES-CreERT2-WPRE-pA expression cassette were knock into the Atp4b gene start codon site to generate Atp4b-IRES-CreERT2(Stock No. NM-KI-210118) mice. ATP4B could serve as a tumor suppressor in the tumorigenesis and progression. This strain is useful in studying the function of gastric parietal cells in gastric epithelial homeostasis. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cre-expressing cells after tamoxifen treatment.

Mice

hCTLA-4(2)

Strain Name：C57BL/6Smoc-Ctla4em2(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190038

Extracellular domain of mouse Ctla4 gene was replaced by human CTLA4 gene. While hCTLA4(Stock No.NM-HU-00014) mice function similarly to hCTLA4(2) mice,for more detailed information please contact our technical advisor.

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