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Models

About 42,463 results
Mice

hTPBG

Strain Name：C57BL/6Smoc-Tpbgtm1(hTPBG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200239
Validation Data：Presence

The endogenous mice Tpbg gene was replaced by human TPBG gene.

Mice

hPD-1/hPD-L1/hTIM3

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)Havcr2tm1(hHAVCR2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200264

hTIM3（NM-HU-00054）,hPD-1（NM-HU-00015）,hPD-L1（NM-HU-00062）were crossed together to generate hPD-1/hPD-L1/hTIM3 mice

Mice

hPD-L1(2)/hCCR8

Strain Name：C57BL/6Smoc-Cd274tm2(hPD-L1)Ccr8tm1(hCCR8)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210401

hPD-1(2)(NM-HU-190039) was crossed with hCCR8(NM-HU-190053) to generate hPD-L1(2)/hCCR8 mice.

Mice

Aadat-Flox

Strain Name：C57BL/6Smoc-Aadatem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253922

These mice carry loxP sites flanking exon 2 of Aadat gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadat gene.

Mice

Procr-DreERT2

Strain Name：C57BL/6Smoc-Procrem1(kozak-DreER-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200201

A kozak-DreER-WPRE-pA expression cassette was knocked into the Procr gene start codon site.

Mice

hOX40/hCTLA-4

Strain Name：C57BL/6Smoc-Tnfrsf4tm3(hTNFRSF4)Ctla4tm1(hCTLA4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00105

These mice are OX40 and CTLA4 double knockin mouse models which can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

Aadacl4fm1-Flox

Strain Name：C57BL/6Smoc-Aadacl4fm1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253852

These mice carry loxP sites flanking exon 2 of Aadacl4fm1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadacl4fm1 gene.

Mice

Adcy5-KO

Strain Name：C57BL/6Smoc-Adcy5em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 3 of Adcy5 gene was deleted to generate Adcy5 knockout mice.

Mice

hLYPD3

Strain Name：C57BL/6Smoc-Lypd3tm1(hLYPD3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200248

The endogenous mice Lypd3 gene was replaced by human LYPD3 gene.

Mice

Tff1-2A-CreERT2

Strain Name：C57BL/6Smoc-Tff1em1(2A-CreERT2-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200244
Validation Data：Presence

A 2A-CreERT2-polyA expression cassette was knocked into the Tff1 gene start codon site.

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