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Models

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Mice

hPD-1/Cd8a-IRES-Akaluc-2A-EGFP

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd8aem1(V5-IRES-Akaluc-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210373

hPD-1(NM-HU-00015) was crossed with Cd8a-IRES-Luc-2A-EGFP(NM-KI-18030) to generate hPD-1/Cd8a-IRES-Luc-2A-EGFP mice

Mice

h4-1BB(2)/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210357

h4-1BB(2)(NM-HU-190077), hPD-L1(NM-HU-00062) and hPD-1(NM-HU-00015) was crossed together to generate h4-1BB(2)/hPD-1/hPD-L1 mice.

Mice

H11-CAG-LSL-Myc

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-Myc)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00039

The c-Myc gene (also known as Myc) is abnormally expressed in many tumors and plays a critical role in the regulation of cell proliferation, growth and metabolism, gene instability, stimulation of angiogenesis, malignant transformation, cell differentiation and apoptosis. These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven Myc oncogene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination. Myc is expressed when bred to mice that express Cre recombinase.

Mice

hANGPTL3(4)

Strain Name：C57BL/6Smoc-Angptl3em1(hANGPTL3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210036

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(3)(Stock No.NM-HU-210037) mice function similarly to hANGPTL3(2) mice, for more detailed information please contact our technical advisor.

Mice

hANGPT2

Strain Name：C57BL/6Smoc-Angpt2tm1(hANGPT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200247

The endogenous mice Angpt2 gene was replaced by human ANGPT2 gene.

Mice

hCD38(2)

Strain Name：C57BL/6Smoc-Cd38em2(CD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190059

The endogenous mouse Cd38 gene was replaced by human CD38 gene. While hCD38 mice(Stock No.NM-HU-00113）have been pulled from shelves for some reasons.

Mice

hAHR

Strain Name：C57BL/6Smoc-Ahrem1(hAHR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200252

The endogenous mice Ahr gene was replaced by human AHR gene.

Mice

Ly6g-Cre-2A-tdTomato

Strain Name：C57BL/6Smoc-Ly6gem2(iCre-P2A-tdTomato-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200219

A iCre-P2A-tdTomato-polyA expression cassette was knocked into the Ly6g gene start codon site.

Mice

hCCR4(2)

Strain Name：C57BL/6Smoc-Ccr4tm1(hCCR4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215015

The endogenous mice Ccr4 gene was replaced by human CCR4 gene.

Mice

hAQP4

Strain Name：C57BL/6Smoc-Aqp4em1(hAQP4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210001

The endogenous mice Aqp4 gene was replaced by human AQP4 gene

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