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Models

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Mice

Il33-KO(2)

Strain Name：C57BL/6Smoc-Il33em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190436

Il33-KO(2) mice(Stock No.NM-KO-190436) carry a knockout allele derived from the targeted deletion of exon 3-7. While Il33-KO mice(Stock No.NM-KO-00099) have been pulled from shelves for some reasons and Il33-KO(3) mice(Stock No.NM-KO-210206) carrying the exon 2 deletion.

Mice

Abcc8-KO(2)

Strain Name：C57BL/6Smoc-Abcc8em2Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-225150

exon 8-16 of Abcc8 gene was deleted to generate Abcc8 knockout mice.

Mice

A4galt-KO

Strain Name：C57BL/6Smoc-A4galtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200001

Exon 3 of A4galt gene was deleted to generate A4galt knockout mice.

Mice

hOX40/hCTLA-4

Strain Name：C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4)Ctla4em1(hCTLA4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00105

These mice are OX40 and CTLA4 double knockin mouse models which can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hTPBG

Strain Name：C57BL/6Smoc-Tpbgem1(hTPBG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200239

The endogenous mice Tpbg gene was replaced by human TPBG gene.

Mice

hLILRB4

Strain Name：C57BL/6Smoc-Lilrb4aem1(hLILRB4 )Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210024

The endogenous mice Lilrb4a gene was completely or partially replaced by human LILRB4 gene via CRISPR/Cas9 mediated recombination.

Mice

Car4-DreERT2

Strain Name：C57BL/6Smoc-Car4em1(DreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200193

A DreERT2-Wpre-pA expression cassette was knocked into the Car4 gene start codon site.

Mice

hIL21/hIL21R

Strain Name：C57BL/6Smoc-Il21tm1(hIL21)Il21rtm1(hIL21R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220038

hIL21(NM-HU-200255) were crossed with hIL21R(NM-HU-210031) to generate hIL21/hIL21R mice.

Mice

R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190065

These mice harbor a CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

C1qa-KO

Strain Name：C57BL/6Smoc-C1qaemSmoc
Strain State：Repository Live | Cat. NO.：NM-KO-210110

exon 3 of C1qa gene was deleted to generate C1qa knockout mice.

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