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Models

About 42,463 results
Mice

Lrp1-Flox

Strain Name：C57BL/6Smoc-Lrp1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-2101319

These mice carry loxP sites flanking exon 7-8 of Lrp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lrp1 gene.

Mice

Angptl6-KO

Strain Name：C57BL/6Smoc-Angptl6em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201240

Exon 3 of Angptl6 gene was deleted to generate Angptl6 knockout mice.

Mice

hIL18

Strain Name：C57BL/6Smoc-Il18tm1(hIL18)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210038
Validation Data：Presence

The endogenous mice Il18 gene was replaced by human IL18 gene.

Mice

Gpr132-KO

Strain Name：C57BL/6Smoc-Gpr132em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200979

Exon 3 of Gpr132 gene was deleted to generate Gpr132 knockout mice.

Mice

hCD3EDG/hCD28

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220113
Validation Data：Presence

hCD3EDG(NM-HU-220120) mice were crossed with hCD28(NM-HU-190011) to generate hCD3EDG/hCD28 mouse

Mice

hF12

Strain Name：C57BL/6Smoc-F12tm1(hF12)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210017
Validation Data：Presence

The endogenous mice F12 gene was replaced by human F12 gene.

Mice

hICOS

Strain Name：C57BL/6Smoc-Icostm1(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00052
Validation Data：Presence

The endogenous mouse Icos gene was replaced by human ICOS gene. While hICOS(2)(Stock No.NM-HU-190030) mice function similarly to hICOS mice,for more detailed information please contact our technical advisor.

Mice

Foxp3-DreERT2

Strain Name：C57BL/6Smoc-Foxp3em5(IRES-DreER)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200198

A IRES-DreER expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190065

These mice harbor a CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

hSIRPA(2)/hCD47

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47tm1(hCD47)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000111
Validation Data：Presence

This SIRPA and CD47 double Knock-in strain is established by crossing hSIRPA and hCD47 mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.While hSIRPA/hCD47 (Stock No.NM-HU-190019) have been pulled from shelves for some reasons.

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