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Models

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Mice

hTIGIT/hCCR8

Strain Name:C57BL/6Smoc-Tigitem1(hTIGIT)Ccr8em1(hCCR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210426

hTIGIT(NM-HU-00053) was crossed with hCCR8(NM-HU-190053) to generate hTIGIT/hCCR8 mice.

Mice

R26-CreERT2

Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200041

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA cassette in the Rosa26 locus generated by homologous recombination. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in multiple tissues after tamoxifen treatment.

Mice

Xirp1-KO

Strain Name:C57BL/6Smoc-Xirp1em1Smoc
Strain State:Developing | Cat. NO.:TBD

Exon 2 of Xirp1 gene was deleted to generate Xirp1 knockout mice.

Mice

hPD-1/hPD-L1/hCD73(2)

Strain Name:C57BL/6Smoc-Pdcd1em1(hPD-1)Cd274em1(hPD-L1)Nt5eem2(hNT5E)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210410

hPD-1(NM-HU-00015) was crossed with hPD-L1/hCD73(2)(NM-HU-210356) to generate hPD-1/hPD-L1/hCD73(2) mice.

Mice

Isl1-Cre

Strain Name:C57BL/6Smoc-Isl1em1(iCre-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200126

A iCre-WPRE-pA expression cassette was knocked into the Isl1 gene start codon site.

Mice

hCD3EDG/hCD40

Strain Name:C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd40em1(hCD40) /Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220116

hCD3EDG(NM-HU-220120) mice were crossed with hCD40(NM-HU-00076) to generate hCD3EDG//hCD40 mice.

Mice

Abcb8-Flox

Strain Name:C57BL/6Smoc-Abcb8em1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of Abcb8 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Abcb8 gene.

Mice

hF11

Strain Name:C57BL/6Smoc-F11em1(hF11)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210015

The endogenous mice F11 gene was replaced by human F11 gene

Mice

hIL13/hOX40

Strain Name:C57BL/6Smoc-Il13em2(hIL13)Tnfrsf4em1(hTNFRSF4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220024

hIL13(NM-HU-190069) was crossed with hOX40(NM-HU-00041) to generate hIL13/hOX40 mice.

Mice

hSIRPA(2)/hCD47/hCTLA-4

Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Ctla4em1(hCTLA4) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210368

hCTLA4(NM-HU-00014) was crossed with hSIRPA(2)/hCD47(NM-HU-2000111)to generate hSIRPA(2)/hCD47/hCTLA4 mice

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