Welcome to Advanced Search

Models

About 42,463 results
Mice

hPD-L1/hCTLA-4

Strain Name：C57BL/6Smoc-Ctla4tm1(hCTLA4)Cd274tm1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00102
Validation Data：Presence

hPD-L1(NM-HU-00062) was crossed with hCTLA4(NM-HU-00014)to generate hPD-1/hCTLA4 mice

Mice

AA467197-Flox

Strain Name：C57BL/6Smoc-AA467197em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253746

These mice carry loxP sites flanking exon 1-3 of AA467197 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of AA467197 gene.

Mice

Casp8-Flox

Strain Name：C57BL/6Smoc-Casp8em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-190003

These Casp8 flox mice possess loxP sites flanking exons 4. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

A4gnt-Flox

Strain Name：C57BL/6Smoc-A4gntem1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-253848

These mice carry loxP sites flanking exon 1-2 of A4gnt gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A4gnt gene.

Mice

Slc6a11-CreERT2

Strain Name：C57BL/6Smoc-Slc6a11em1(CreERT2-polyA(SV40)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200130
Validation Data：Presence

A CreERT2-polyA expression cassette was knocked into the Slc6a11 gene start codon site. Slc6a11 encodes GAT3 (Gabt4), a sodium-dependent transporter that uptakes the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which ends the GABA neurotransmission. When Slc6a11-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLC6A11positive cells. Defects in Slc6a11 may result in epilepsy or behavioral and intellectual defects.

Mice

C9orf72-KO

Strain Name：C57BL/6Smoc-C9orf72em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201246

Exon 4-5 of C9orf72 gene was deleted to generate C9orf72 knockout mice.

Mice

hCD40/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Cd40tm1(hCD40)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210406

hPD-1/hPD-L1(NM-HU-00100) was crossed with hCD40（NM-HU-00076）to generate hCD40/hPD-1/hPD-L1 mice

Mice

hFCRN(3)

Strain Name：C57BL/6Smoc-Fcgrttm3(hFCGRT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000032

The endogenous mouse Fcgrt gene was replaced by human FCGRT gene. While hFCRN(Stock No.NM-HU-00109）and hFCRN(2)(Stock No.NM-HU-190070) mice function similarly to hFCRN(3) mice,for more detailed information please contact our technical advisor.

Mice

hNECTIN4

Strain Name：C57BL/6Smoc-Nectin4tm1(hNECTIN4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210016
Validation Data：Presence

The endogenous mice Nectin4 gene was replaced by human NECTIN4 gene.

Mice

Dmd-Q995X

Strain Name：C57BL/6Smoc-Dmdem1(Q995X)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18026
Validation Data：Presence

These mice carry a p.Q995X mutation in Dmd gene.

Email Back to top