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Models

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Mice

hIL11/hIL11RA

Strain Name：C57BL/6Smoc-Il11em1(hIL11)Il11ra1tm1(hIL11RA)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210372

hIL11(NM-HU-204981) was crossed with hIL11RA (NM-HU-204982) to generate hIL11/hIL11RA mice.

Mice

hSIGLEC8

Strain Name：C57BL/6Smoc-Sigleceem1(hSIGLEC8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204983

The endogenous mice Siglece gene was replaced by human SIGLEC8 gene. While hSIGLEC8(2)(Stock No.NM-HU-210033) mice function similarly to hSIGLEC8 mice,for more detailed information please contact our technical advisor.

Mice

Tie1-2A-Cre

Strain Name：C57BL/6Smoc-Tie1em1(2A-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-18023

A 2A-Cre coexpression cassette is inserted befor the stop codon of mouse Tie1 gene via homologous recombination to establish a tamoxifen inducible Tie1-Cre tool stain. This strain can be used to knockout target gene in Tie1+ cells when crossed with mice which carry loxp sites flanking target gene.

Mice

hCRLF2

Strain Name：C57BL/6Smoc-Crlf2tm1(hCRLF2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210028

The endogenous mice Crlf2 gene was completely or partially replaced by human CRLF2 gene via ESC targeting.

Mice

hFCRN(2)

Strain Name：C57BL/6Smoc-Fcgrtem2(hFCGRT)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190070

The endogenous mouse Fcgrt gene was replaced by human FCGRT gene.While hFCRN(Stock No.NM-HU-00109) and hFCRN(3)(Stock No.NM-HU-2000032）mice function similarly to hFCRN(2) mice,for more detailed information please contact our technical advisor.

Mice

hIL6ST

Strain Name：C57BL/6Smoc-Il6stem1(hIL6ST)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204980

The endogenous mice Il6st gene was replaced by human IL6ST gene.

Mice

hIL21R/hIL2RG

Strain Name：C57BL/6Smoc-Il21rtm1(hIL21R)Il2rgem1(IL2RG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220004

hIL21R(NM-HU-210031) was crossed with hIL2RG(NM-HU-200007) to generate hIL21R/hIL2RG mice.

Mice

hPD-L1(2)/hCD28

Strain Name：C57BL/6Smoc-Cd274em2(hPD-L1)Cd28em2(hCD28)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210370

hPD-L1(2)(NM-HU-190039) was crossed with hCD28(NM-HU-190011）to generate hPD-L1(2)/hCD28 mice

Mice

hHER3

Strain Name：C57BL/6Smoc-Erbb3tm1(hERBB3)Smoc
Strain State：Developing | Cat. NO.：NM-HU-200234

The endogenous mice Erbb3 gene was replaced by human HER3 gene.

Mice

hIL18

Strain Name：C57BL/6Smoc-Il18tm1(hIL18)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210038

The endogenous mice Il18 gene was replaced by human IL18 gene.

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