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Models

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Mice

hIL21

Strain Name：C57BL/6Smoc-Il21tm1(hIL21)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200255
Validation Data：Presence

The endogenous mice Il21 gene was replaced by human IL21 gene.

Mice

hCXCR6

Strain Name：C57BL/6Smoc-Cxcr6tm(hCXCR6)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215001
Validation Data：Presence

The endogenous mice Cxcr6 gene was replaced by human CXCR6 gene.

Mice

hSIGLEC8

Strain Name：C57BL/6Smoc-Siglecetm1(hSIGLEC8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204983

The endogenous mice Siglece gene was replaced by human SIGLEC8 gene. While hSIGLEC8(2)(Stock No.NM-HU-210033) mice function similarly to hSIGLEC8 mice,for more detailed information please contact our technical advisor.

Mice

Mertk-KO

Strain Name：C57BL/6Smoc-Mertkem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200362

Exon 2 of Mertk gene was deleted to generate Mertk knockout mice.

Mice

hTSLP/hIL17RA

Strain Name：C57BL/6Smoc-Tslptm2(hTSLP)Il17rtm1(hIL17R)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200269

hTSLP（NM-HU-2000064）was crossed with hIL17R（NM-HU-190049）to generate hTSLP/hIL17RA mice

Mice

hGDF15

Strain Name：C57BL/6Smoc-Gdf15tm(hGDF15)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215002
Validation Data：Presence

The endogenous mice Gdf15 gene was replaced by human GDF15 gene.

Mice

hPD-1/hLAG3

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Lag3tm1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00101

hPD-1(NM-HU-00015) was crossed with hLAG3(NM-HU-00049)to generate hPD-1/hLAG3 mice

Mice

Nkx2-5-IRES-Cre

Strain Name：C57BL/6Smoc-Nkx2-5em1(IRES-Cre-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200152
Validation Data：Presence

A IRES-Cre-WPRE-polyA expression cassette was knocked into the Nkx2-5 gene stop codon site.

Mice

Uox-KO(2)

Strain Name：C57BL/6Smoc-Uoxem1Smoc  
Strain State：Repository Live | Cat. NO.：NM-KO-191205
Validation Data：Presence  |  Publications：1piece

Uox-KO(2) mice(Stock No.NM-KO-191205）carry a knockout allele derived from the targeted deletion of exon 3-4.

Mice

Bhlha15-CreERT2(2)

Strain Name：C57BL/6Smoc-Bhlha15em2(kozak-CreERT2-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200158

A kozak-CreERT2-WPRE-polyA expression cassette was knocked into the Bhlha15 gene start codon site. While Bhlha15-CreERT2 (Stock No. NM-KI-200080) mice were generated through replacing the coding region of Bhlha15 gene with a CreERT2 expression cassette.

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