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Mice

Avpr1a-KO

Strain Name：C57BL/6Smoc-Avpr1aem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200043

Exon 1-2 of Avpr1a gene was deleted to generate Avpr1a knockout mice.

Mice

C4b-KO

Strain Name：C57BL/6Smoc-C4bem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190761

Exon 3 of C4b gene was deleted to generate C4b knockout mice.

Mice

Bmal1-Flox

Strain Name：C57BL/6Smoc-Bmal1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200063

These mice carry loxP sites flanking exon 8 of Bmal1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Bmal1 gene.

Mice

R26-CAG-2xKRAB-dCas9-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-Loxp-2xKRAB-dCas9-IRES-EGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-18007

These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted.

Mice

Casp8-Flox

Strain Name：C57BL/6Smoc-Casp8em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-190003

These Casp8 flox mice possess loxP sites flanking exons 4. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

Mice

Apc-Flox

Strain Name：C57BL/6Smoc-Apctm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200013

These mice carry loxP sites flanking exon 15 of Apc gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Apc gene.

Mice

Wt1-CreERT2

Strain Name：C57BL/6Smoc-Wt1em1(CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200127

A CreERT2-WPRE-pA expression cassette was knocked into the Wt1 gene start codon site.

Mice

hPD-1/hIL1B

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Il1btm3(hIL1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210018

hPD-1(NM-HU-00015) was crossed with hIL1B(NM-HU-190047) to generate hPD-1/hIL1B mice

Mice

hHLA-DPB1*04: 01

Strain Name：C57BL/6Smoc-H2-Ab1em1(hHLA-DPB1*04: 01)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210011

The endogenous mice H2-Ab1 gene was replaced by human HLA-DPB1*04:01 gene.

Mice

hCTLA-4/hTIGIT

Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4)Tigitem1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210399

hCTLA4(NM-HU-00014) was crossed with hTIGIT(NM-HU-00053) to generate hCTLA4/hTIGIT mice.

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