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Models

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Mice

hIL21R

Strain Name：C57BL/6Smoc-Il21rtm1(hIL21R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210031
Validation Data：Presence

The endogenous mice Il21r gene was completely or partially replaced by human IL21R gene via ESC targeting.

Mice

hLILRB4

Strain Name：C57BL/6Smoc-Lilrb4atm1(hLILRB4 )Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210024
Validation Data：Presence

The endogenous mice Lilrb4a gene was completely or partially replaced by human LILRB4 gene via CRISPR/Cas9 mediated recombination.

Mice

R26-hCD46-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-hCD46-IRES-tdTomato-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190087
Validation Data：Presence

These mice harbor a SA-human CD46-IRES-tdTomato-polyA cassette in the Rosa26 locus generated by homologous recombination.

Mice

hCD3EDG/hCD28/hCD38(2)

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd28tm2(hCD28)Cd38tm2(hCD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220115

hCD3EDG/hCD28(NM-HU-220113) mice were crossed with hCD3EDG/hCD38(NM-HU-220114) mice to generate hCD3EDG/hCD28/hCD38(2) mice.

Mice

hPD-L1(E3-4)

Strain Name：C57BL/6Smoc-Cd274tm2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190039
Validation Data：Presence

Extracellular domain of mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene. While hPD-L1(Stock No.NM-HU-00062) mice function similarly to hPD-L1(2) mice,for more detailed information please contact our technical advisor.

Mice

hOX40L

Strain Name：C57BL/6Smoc-Tnfsf4tm1(hTNFSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00070

The endogenous mouse Tnfsf gene was replaced by human TNFSF4（OX-40L） gene . While hOX40L(2)(Stock No.NM-HU-200005) mice function similarly to hOX40L mice,for more detailed information please contact our technical advisor.

Mice

hCXCR5

Strain Name：C57BL/6Smoc-Cxcr5tm2(hCXCR5)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215007

The endogenous mice Cxcr5 gene was replaced by human CXCR5 gene.

Mice

hCD2

Strain Name：C57BL/6Smoc-Cd2tm1(hCD2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-204986
Validation Data：Presence

The endogenous mice Cd2 gene was replaced by human CD2 gene.

Mice

hCD44

Strain Name：C57BL/6Smoc-Cd44tm(hCD44)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215003
Validation Data：Presence

The endogenous mice Cd44 gene was replaced by human CD44 gene.

Mice

hIL2RA/hIL2RB/hIL2RG

Strain Name：C57BL/6Smoc-Il2ratm1(hIL2RA)Il2rgtm1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210414
Validation Data：Presence

hIL2RA(NM-HU-190064) was crossed with hIL2RG/hILRB(NM-HU-210354) to generate hIL2RA/hIL2RB/hIL2RG mice.

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