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Models

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Mice

hPVRIG

Strain Name：C57BL/6Smoc-Pvrigem1(hPVRIG)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210008

The endogenous mice Pvrig gene was replaced by human PVRIG gene While hPVRIG(2)(Stock No.NM-HU-215013) mice function similarly to hPVRIG mice, for more detailed information please contact our technical advisor.

Mice

Aldh7A1-KO

Strain Name：C57BL/6Smoc-Aldh7A1em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 2-5 of Aldh7A1 gene was deleted to generate Aldh7A1 knockout mice.

Mice

hGCGR

Strain Name：C57BL/6Smoc-Gcgrem(hGCGR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215004

The endogenous mice Gcgr gene was replaced by human GCGR gene.

Mice

hHLA-A11.1

Strain Name：C57BL/6Smoc-H2-K1tm1(hHLA-A*1101)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-204987

The endogenous mice H2-K1 gene was replaced by human HLA-A11.1 gene.

Mice

Ins2-C96Y

Strain Name：C57BL/6Smoc-Ins2em3(C96Y)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190096

These mice carry a p.C96Y mutation of Ins2 gene.

Mice

Gad2-IRES-Cre

Strain Name：C57BL/6Smoc-Gad2em1(IRES-iCre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200078

A IRES-iCre-pA expression cassette was knocked into the Gad2 gene stop codon site.

Mice

hIL11RA

Strain Name：C57BL/6Smoc-Il11ra1tm1(hIL11RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204982

The endogenous mice Il11ra1 gene was replaced by human IL11RA gene.

Mice

hTROP2

Strain Name：C57BL/6Smoc-Tacstd2em(hTACSTD2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215022

The endogenous mice Tacstd2 gene was replaced by human TACSTD2 gene.

Mice

Dmd-Q995X

Strain Name：C57BL/6Smoc-Dmdem1(Q995X)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18026

These mice carry a p.Q995X mutation in Dmd gene.

Mice

Bhlha15-CreERT2

Strain Name：C57BL/6Smoc-Bhlha15em1(CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200080

The coding region of Bhlha15 gene was replaced by a CreERT2 expression cassette.Besides,a kozak-CreERT2-WPRE-polyA expression cassette were knock into the Bhlha15 gene start codon site to generate Bhlha15-CreERT2(2)(Stock No. NM-KI-200158) mice. Bhlha15(basic helix-loop-helix family member a15) is also known as Mist1. The gene product is involved in controlling exocrine secretion from the pancreas, small intestine and stomach. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Bhlha15.

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