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Mice

Angptl6-KO

Strain Name：C57BL/6Smoc-Angptl6em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201240

Exon 3 of Angptl6 gene was deleted to generate Angptl6 knockout mice.

Mice

hCD40/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Cd40em1(hCD40)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210406

hPD-1/hPD-L1(NM-HU-00100) was crossed with hCD40（NM-HU-00076）to generate hCD40/hPD-1/hPD-L1 mice

Mice

hTIGIT(3)

Strain Name：C57BL/6Smoc-Tigittm3(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200244

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(Stock No.NM-HU-00053) mice function similarly to hTIGIT（3） mice ,for more detailed information please contact our technical advisor.

Mice

hTNFR2/hIL2RA

Strain Name：C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Il2ratm1(hIL2RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210408

hTNFRSF1B(NM-HU-190010) was crossed with hIL2RA(NM-HU-190064) to generate hTNFRSF1B/hIL2RA mice.

Mice

Slco1c1-2A-CreERT2

Strain Name：C57BL/6Smoc-Slco1c1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200262

2A-CreERT2 expression cassette was knocked into the Slco1c1 gene stop codon site. Slco1c1 encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. When Slco1c1-2A-CreERT2 mice are bred with mice containing loxP-flanked sequence, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in SLCO1C1 positive cells.

Mice

C9orf72-KO

Strain Name：C57BL/6Smoc-C9orf72em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201246

Exon 4-5 of C9orf72 gene was deleted to generate C9orf72 knockout mice.

Mice

Col1a1-TRE3G-dCas9-VPR-EGFP

Strain Name：C57BL/6Smoc-Col1a1em1(TRE3G-dCas9-VPR-eGFP-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00123

These mice harbor a TRE3G-dCas9-VPR(VP64-p65-Rta)-eGFP-pA tetracycline-controlled transcriptional activation cassette in mouse Col1a1 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Mice

Arg1-KO

Strain Name：C57BL/6Smoc-Arg1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-200629

Exon 3 of Arg1 gene was deleted to generate Arg1 knockout mice.

Mice

hCD44

Strain Name：C57BL/6Smoc-Cd44em(hCD44)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215003

The endogenous mice Cd44 gene was replaced by human CD44 gene.

Mice

hHLA-A2.22

Strain Name：C57BL/6Smoc-H2-D1em1(hHLA-A2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-204988

The endogenous mice H2-D1 gene was replaced by human HLA-A2 gene.

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