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Models

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Mice

Adk-KO

Strain Name：C57BL/6Smoc-Adkem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201237

Exon 4 of Adk gene was deleted to generate Adk knockout mice.

Mice

Siglecf-DreERT2

Strain Name：C57BL/6Smoc-Siglecfem1(kozak-DreER-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200202

A kozak-DreER-WPRE-pA expression cassette was knocked into the Siglecf gene start codon site.

Mice

Lyz2-2A-CreERT2

Strain Name：C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18018
Validation Data：Presence

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

H11-CAG-EGFP

Strain Name：C57BL/6Smoc-Igs2 em1(CAG-EGFP-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00066

These mice harbor a CAG promoter-driven EGFP report gene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination.

Mice

hTIGIT/hTNFR2

Strain Name：C57BL/6Smoc-Tigittm3(hTIGIT)Tnfrsf1btm2(hTNFRSF1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210371

hTIGIT(3)(NM-HU-200244) was crossed with hTNFRSF1B(NM-HU-190010）to generate hTIGIT(3)/hTNFRSF1B mice

Mice

Cd68-2A-Cre

Strain Name：C57BL/6Smoc-Cd68em5(2A-Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200192
Validation Data：Presence

This Cd68-Cre tool mouse model was established by inserting a 2A-Cre-WPRE-polyA co-expression cassette into the stop codon of Cd68 gene .

Mice

hCD28/hCD38(2)

Strain Name：C57BL/6Smoc-Cd28tm2(hCD28)Cd38tm2(CD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210350

hCD38(NM-HU-190059) was crossed with hCD28(NM-HU-190011) to generate hCD28/hCD38 mice.

Mice

Sox9-IRES-CreERT2

Strain Name：C57BL/6Smoc-Sox9em(IRES-CreERT2-SV40pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-204996
Validation Data：Presence  |  Publications：1piece

IRES-CreERT2-SV40pA expression cassette was knocked into the Sox9 gene .

Mice

Tmem119-2A-DTRGFP

Strain Name：C57BL/6Smoc-Tmem119em4(P2A-DTRGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200235

A P2A-DTRGFP expression cassette was knocked into the Tmem119 gene stop codon site.

Mice

hGCGR

Strain Name：C57BL/6Smoc-Gcgrtm(hGCGR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215004
Validation Data：Presence

The endogenous mice Gcgr gene was replaced by human GCGR gene.

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