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Mice

MHC Class II (I-A/I-E) -KO

Strain Name：C57BL/6Smoc-H2-Ab1em1H2-Aaem1 H2-Eb1em1H2-Eb2em1H2-Ea-ps em1 Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18032

All sequences from the upstream of mouse H2-Ab1 gene exon 2 to the upstream of the H2-Ea-ps gene exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models. These MHC class II molecule-deficient mice were on the C57BL/6J genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

hOX40(2)/hOX40L/hICOS

Strain Name：C57BL/6J-Tnfrsf4 em1(hTNFRSF4)Tnfsf4 em2(hTNFSF4)Icos em1(hICOS )Smoc
Strain State：Developing | Cat. NO.：NM-HU-252545

ICOS humanization was performed on the background of hOX40(2)/hOX40L mice using homologous recombination

Mice

C57BL/6

Strain Name：C57BL/6Smoc
Strain State：Repository Live | Cat. NO.：SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

Apoe-KO(2)

Strain Name：C57BL/6Smoc-Apoeem5Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190565

Apoe-KO(2) mice (Stock No.NM-KO-190565) carry a knockout allele derived from the targeted deletion of exon 2-4. While Apoe-KO mice (Stock No.NM-KO-00033) have been pulled from shelves for some reasons.

Mice

hEGFR

Strain Name：C57BL/6Smoc-Egfrtm1(hEGFR)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200227

The endogenous mice Egfr gene was replaced by human EGFR gene. While hEGFR(2)(Stock No.NM-HU-200232) mice have been pulled from shelves for some reasons.

Mice

A26c3-Flox

Strain Name：C57BL/6Smoc-A26c3em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of A26c3 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A26c3 gene.

Mice

Adcy5-KO

Strain Name：C57BL/6Smoc-Adcy5em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 3 of Adcy5 gene was deleted to generate Adcy5 knockout mice.

Mice

A1bg-Flox

Strain Name：C57BL/6Smoc-A1bgem1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of A1bg gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A1bg gene.

Mice

A1Cf-KO

Strain Name：C57BL/6Smoc-A1Cfem1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 4 of A1Cf gene was deleted to generate A1Cf knockout mice.

Mice

A2m-Flox

Strain Name：C57BL/6Smoc-A2mem1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of A2m gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2m gene.

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