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Models

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Mice

R26-CAG-2xKRAB-dCas9-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-Loxp-2xKRAB-dCas9-IRES-EGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18007
Validation Data：Presence

These mice harbor a CAG-LSL-2xKRAB-dCas9-IRES-EGFP-WPRE-pA conditional expression cassette in mouse Rosa26 loci via homologous recombination. This strain can be used in CRISPR mediated target gene transcriptional inhibition (CRISPRi). The loxp-stop-loxp cassette was deleted.

Mice

hCD3EDG/hTPBG

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Tpbgtm1(hTPBG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220111

hCD3EDG(NM-HU-220120) mice were crossed with hTPBG(NM-HU-200239) mice to generate hCD3EDG/hTPBG mice

Mice

Atrn-2A-Cre

Strain Name：C57BL/6Smoc-Atrnem(2A-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-215077

2A-Cre expression cassette was knocked into the Atrn gene .

Mice

Abcc2-KO

Strain Name：C57BL/6Smoc-Abcc2em3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18017

Exon4-6 of Abcc2 gene were deleted to generate Abcc2 knockout mice.

Mice

Gp1ba-2A-Cre

Strain Name：C57BL/6Smoc-Gp1baem1(T2A-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200172
Validation Data：Presence

A T2A-iCre expression cassette was knocked into the Gp1ba gene stop codon site.

Mice

Itgam-IRES-hCD89

Strain Name：C57BL/6Smoc-Itgamtm1(IRES-hCD89-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200063
Validation Data：Presence  |  Publications：1piece

A IRES-hCD89-WPRE-polyA expression cassette was knocked into the Itgam gene stop codon site.

Mice

Isl1-Dre

Strain Name：C57BL/6Smoc-Isl1em1(Dre-Wpre-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200177

A Dre-Wpre-polyA expression cassette was knocked into the Isl1 gene start codon site.

Mice

Ins2-CreERT2

Strain Name：C57BL/6Smoc-Ins2em(CreERT2)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225022
Validation Data：Presence

CreERT2 expression cassette was knocked into the Ins2 gene .

Mice

hCD3EDG/hCD40/h4-1BB(2)

Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd40tm1(hCD40)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220117

hCD3EDG/hCD40(NM-HU-220116) mice were crossed with hCD3EDG/h4-1BB(2)(NM-HU-220110) to generate hCD3EDG/hCD40/h4-1BB(2) mice.

Mice

Hif1a-Flox

Strain Name：C57BL/6Smoc-Hif1atm1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-190065
Publications：1piece

These mice carry loxP sites flanking exon 2 of Hif1a gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Hif1a gene.

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