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Models

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Mice

Siglecf-DreERT2

Strain Name：C57BL/6Smoc-Siglecfem1(kozak-DreER-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200202

A kozak-DreER-WPRE-pA expression cassette was knocked into the Siglecf gene start codon site.

Mice

Lyz2-2A-CreERT2

Strain Name：C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18018
Validation Data：Presence

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

H11-CAG-EGFP

Strain Name：C57BL/6Smoc-Igs2 em1(CAG-EGFP-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00066

These mice harbor a CAG promoter-driven EGFP report gene. The targeted mutation was inserted into the Hipp11(H11) locus by homologous recombination.

Mice

hTIGIT/hTNFR2

Strain Name：C57BL/6Smoc-Tigittm3(hTIGIT)Tnfrsf1btm2(hTNFRSF1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210371

hTIGIT(3)(NM-HU-200244) was crossed with hTNFRSF1B(NM-HU-190010）to generate hTIGIT(3)/hTNFRSF1B mice

Mice

Pax8-Cre

Strain Name：C57BL/6Smoc-Pax8em1(Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200151
Validation Data：Presence

A Cre-WPRE-polyA expression cassette was knocked into the Pax8 gene start codon site.

Mice

Cd68-2A-Cre

Strain Name：C57BL/6Smoc-Cd68em5(2A-Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200192
Validation Data：Presence

This Cd68-Cre tool mouse model was established by inserting a 2A-Cre-WPRE-polyA co-expression cassette into the stop codon of Cd68 gene .

Mice

hCD33

Strain Name：C57BL/6Smoc-Cd33tm3(CD33)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200002
Validation Data：Presence

The endogenous mouse Cd33 gene was replaced by human CD33 gene .

Mice

hCD28/hCD38(2)

Strain Name：C57BL/6Smoc-Cd28tm2(hCD28)Cd38tm2(CD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210350

hCD38(NM-HU-190059) was crossed with hCD28(NM-HU-190011) to generate hCD28/hCD38 mice.

Mice

Ncr1-2A-CreERT2

Strain Name：C57BL/6Smoc-Ncr1em4(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200004
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

hIL23A

Strain Name：C57BL/6Smoc-Il23atm3(hIL23A)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18030
Validation Data：Presence

The endogenous mouse Il23a gene was replaced by humanIL23A gene .

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