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Models

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Mice

Il7r-Cre

Strain Name：C57BL/6Smoc-Il7rem1(Cre-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200306

Cre-Wpre-pA expression cassette was knocked into the Il7r gene start codon site.

Mice

Avp-IRES-Cre

Strain Name：C57BL/6Smoc-Avpem1(IRES2-Cre-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200142

A IRES2-Cre-WPRE-polyA expression cassette was knocked into the Avp gene stop codon site. Avp encodes arginine vasopressin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying hypertension.

Mice

Cd68-IRES-Cre

Strain Name：C57BL/6Smoc-Cd68em1(IRES-Cre)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200161

A IRES-Cre expression cassette was knocked into the Cd68 gene stop codon site.

Mice

hPD-1/hIL1B

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Il1btm3(hIL1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210018

hPD-1(NM-HU-00015) was crossed with hIL1B(NM-HU-190047) to generate hPD-1/hIL1B mice

Mice

hHLA-DPB1*04: 01

Strain Name：C57BL/6Smoc-H2-Ab1em1(hHLA-DPB1*04: 01)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210011

The endogenous mice H2-Ab1 gene was replaced by human HLA-DPB1*04:01 gene.

Mice

Cd8a-2A-tdTomato-2A-Luc

Strain Name：C57BL/6Smoc-Cd8aem(T2A-tdTomato-P2A-Luciferase)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225025

T2A-tdTomato-P2A-Luciferase expression cassette was knocked into the Cd8a gene .

Mice

hCTLA-4/hTIGIT

Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4)Tigitem1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210399

hCTLA4(NM-HU-00014) was crossed with hTIGIT(NM-HU-00053) to generate hCTLA4/hTIGIT mice.

Mice

Slc34a1-CreERT2

Strain Name：C57BL/6Smoc-Slc34a1em1(CreERT2-SV40pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210110

CreERT2-SV40pA expression cassette was knocked into the Slc34a1 gene .

Mice

hSIRPA(2)/hCD47

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000111

This SIRPA and CD47 double Knock-in strain is established by crossing hSIRPA and hCD47 mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.While hSIRPA/hCD47 (Stock No.NM-HU-190019) have been pulled from shelves for some reasons.

Mice

hSERPINH1

Strain Name：C57BL/6Smoc-Serpinh1tm1(hSERPINH1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225081

The endogenous mouse Serpinh1 gene was replaced by human SERPINH1 gene.

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