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Models

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Mice

hPCSK9

Strain Name：C57BL/6Smoc-Pcsk9tm2(hPCSK9)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00075
Validation Data：Presence  |  Publications：1piece

The endogenous mouse Pcsk9 gene was replaced by human PCSK9 gene .

Mice

hIL11/hIL11RA

Strain Name：C57BL/6Smoc-Il11tm1(hIL11)Il11ra1tm1(hIL11RA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210372
Validation Data：Presence

hIL11(NM-HU-204981) was crossed with hIL11RA (NM-HU-204982) to generate hIL11/hIL11RA mice.

Mice

hCD40L

Strain Name：C57BL/6Smoc-Cd40lgtm1(hCD40L)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000033
Validation Data：Presence

The endogenous mouse Cd40lg gene was replaced by human CD40L gene.

Mice

hCCR8

Strain Name：C57BL/6Smoc-Ccr8tm1(hCCR8) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190053
Validation Data：Presence

The endogenous mouse Ccr8 gene was replaced by human CCR8 gene. While hCCR8(2)(Stock No.NM-HU-2000054) mice function similarly to hCCR8 mice,for more detailed information please contact our technical advisor.

Mice

Scgb1a1-IRES-CreERT2

Strain Name：C57BL/6Smoc-Scgb1a1em1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200129
Validation Data：Presence

A IRES-CreERT2 expression cassette was knocked into the Scgb1a1 gene stop codon site.

Mice

hPD-L2

Strain Name：C57BL/6Smoc-Pdcd1lg2tm1(hPDCD1LG2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190050
Validation Data：Presence

将小鼠Pdcd1lg2基因全部或者部分替换为人源PDCD1LG2，从而表达人或人鼠嵌合PDCD1LG2蛋白，取代小鼠内源Pdcd1lg2蛋白的表达 hPD-L2.

Mice

hCD20

Strain Name：C57BL/6Smoc-Ms4a1tm2(hCD20)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190068

The endogenous mouse Cd20(Ms4a1) gene was replaced by human CD20 gene. While hCD20(2)(Stock No.NM-HU-200114) mice function similarly to hCD20 mice,for more detailed information please contact our technical advisor.

Mice

Hopx-IRES-CreERT2

Strain Name：C57BL/6Smoc-Hopxem1(IRES-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200136
Validation Data：Presence

A IRES-CreERT2 expression cassette was knocked into the Hopx gene stop codon site.

Mice

hCXCR2

Strain Name：C57BL/6Smoc-Cxcr2tm2(hCXCR2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-18025

The endogenous mouse Cxcr2 gene was replaced by human CXCR2 gene.

Mice

A1bg-KO

Strain Name：C57BL/6Smoc-A1bgem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200806

Exon 1-5 of A1bg gene was deleted to generate A1bg knockout mice.

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