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Models

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Mice

Bhlha15-CreERT2

Strain Name：C57BL/6Smoc-Bhlha15em1(CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200080

The coding region of Bhlha15 gene was replaced by a CreERT2 expression cassette.Besides,a kozak-CreERT2-WPRE-polyA expression cassette were knock into the Bhlha15 gene start codon site to generate Bhlha15-CreERT2(2)(Stock No. NM-KI-200158) mice. Bhlha15(basic helix-loop-helix family member a15) is also known as Mist1. The gene product is involved in controlling exocrine secretion from the pancreas, small intestine and stomach. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Bhlha15.

Mice

hMASP2

Strain Name：C57BL/6Smoc-Masp2em1(hMASP2)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000076

The endogenous mouse Masp2 gene was replaced by human MASP2 gene.

Mice

R26-CAG-LSL-hTM6SF2*E167K-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200017

These mice harbor a SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

Mice

hIL33

Strain Name：C57BL/6Smoc-Il33tm2(hIL33)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000069

The endogenous mouse Il33 gene was replaced by human IL33 gene.

Mice

Axin2-2A-DreERT2

Strain Name：C57BL/6Smoc-Axin2em1(P2A-DreERT2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200196

A P2A-DreERT2 expression cassette was knocked into the Axin2 gene stop codon site.

Mice

hPD-L1(E3-4)

Strain Name：C57BL/6Smoc-Cd274em2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190039

Extracellular domain of mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene. While hPD-L1(Stock No.NM-HU-00062) mice function similarly to hPD-L1(2) mice,for more detailed information please contact our technical advisor.

Mice

hSERPINA1

Strain Name：C57BL/6Smoc-Serpina1etm1(hSERPINA1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225055

The endogenous mouse Serpina1e gene was replaced by human SERPINA1 gene.

Mice

Crbn-I391V/Rag2-KO

Strain Name：C57BL/6Smoc-Crbnem1(I391V)Rag2em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210398

Crbn-I391V(NM-KI-200331) was crossed with Rag2-KO(NM-KO-190429) to generate Crbn-I391V/Rag2-KO mice.

Mice

hPD-1/hCD3E

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd3eem1(hCD3E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18021

hPD-1（NM-HU-00015）was crossed with hCD3E（NM-HU-00114）to generate hPD-1/hCD3E。

Mice

hIL2RA

Strain Name：C57BL/6Smoc-Il2ratm1(hIL2RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190064

The endogenous mouse Il2ra gene was replaced by human IL2RA gene.

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