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Models

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Mice

hIL2/hIL2RA/hIL2RB/hIL2RG

Strain Name：C57BL/6Smoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)Il2rgtm1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210415
Validation Data：Presence

hIL2/hIL2RA(NM-HU-200275) was crossed with hIL2RA/hIL2RB/hIL2RG(NM-HU-210414) to generate hIL2/hIL2RA/hIL2RB/hIL2RG mice.

Mice

hAPOE2

Strain Name：C57BL/6Smoc-Apoetm4(hAPOE2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190013
Validation Data：Presence

This APOE2 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE2 corresponding sequence by homologous recombination.

Mice

Akt1-KO

Strain Name：C57BL/6Smoc-Akt1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190741

Exon 2 of Akt1 gene was deleted to generate Akt1 knockout mice.

Mice

hCCR8(2)/hCTLA-4

Strain Name：C57BL/6Smoc-Ccr8tm3(hCCR8)Ctla4tm1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220074
Validation Data：Presence

hCTLA4 (NM-HU-00014) mice were crossed with hCCR8(2) (NM-HU-2000054) mice to generate hCCR8(2)/hCTLA4 mice．

Mice

hCD180

Strain Name：C57BL/6Smoc-Cd180tm1(hCD180)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210006
Validation Data：Presence

The endogenous mice Cd180 gene was replaced by human CD180 gene

Mice

hSIRPA(2)

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18015
Validation Data：Presence

The endogenous mouse Sirpa gene was replaced by human SIRPA gene . While hSIRPA (Stock No.NM-HU-00119) have been pulled from shelves for some reasons.

Mice

Tagln-CreERT2

Strain Name：C57BL/6Smoc-Taglnem(CreERT2)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225006
Validation Data：Presence

CreERT2 expression cassette was knocked into the Tagln gene .

Mice

Calb2-IRES-Cre

Strain Name：C57BL/6Smoc-Calb2em1(IRES-iCre-SV40-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200102
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Calb2 gene stop codon site. Calb2 gene encodes calbindin 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. The protein plays a key role in the nervous system.

Mice

Bmal1-Flox

Strain Name：C57BL/6Smoc-Bmal1em1(flox)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-CKO-200063

These mice carry loxP sites flanking exon 8 of Bmal1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Bmal1 gene.

Mice

hTNFRSF1A

Strain Name：C57BL/6Smoc-Tnfrsf1atm(hTNFRSF1A)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215017

The endogenous mice Tnfrsf1a gene was replaced by human TNFRSF1A gene.

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