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Models

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Mice

hHGF

Strain Name：C57BL/6Smoc-Hgfem1(hHGF)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200235

The endogenous mice Hgf gene was replaced by human HGF gene.

Mice

Aldh1L2-KO

Strain Name：C57BL/6Smoc-Aldh1L2em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 2 of Aldh1L2 gene was deleted to generate Aldh1L2 knockout mice.

Mice

R26-CAG-LNL-CaMPARI

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(CAG-LNL-CaMPARI)-NSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00090

These mice harbor a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven CaMPARI gene. The targeted mutation was inserted into the Gt(ROSA)26Sor locus by homologous recombination.

Mice

Bhlha15-CreERT2(2)

Strain Name：C57BL/6Smoc-Bhlha15em2(kozak-CreERT2-WPRE-polyA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200158

A kozak-CreERT2-WPRE-polyA expression cassette was knocked into the Bhlha15 gene start codon site. While Bhlha15-CreERT2 (Stock No. NM-KI-200080) mice were generated through replacing the coding region of Bhlha15 gene with a CreERT2 expression cassette.

Mice

R26-CAG-LSL-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-Luciferase-2A-EGFP-wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190095

A CAG-LSL-Luciferase-2A-EGFP-wpre-polyA expression cassette was inserted at the Rosa26 locus site.

Mice

Clec4f-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Clec4fem1(IRES-DTRGFP)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200070

A IRES-DTRGFP expression cassette was knocked into the Clec4f gene stop codon site.

Mice

hCD248

Strain Name：C57BL/6Smoc-Cd248em1(hCD248)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-225028

The endogenous mouse Cd248 gene was replaced by human CD248 gene.

Mice

R26-CAG-LSL-dCas9-VPR-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-dCas9-VPR-IRES-EGFP-WPRE-pA)
Strain State：Repository Live | Cat. NO.：NM-KI-18004

These mice harbor a CAG-LSL-dCas9-VPR(VP64-p65-Rta)-eGFP-pA conditional expression cassette in mouse Rosa26 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

Mice

hTNFR2/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220041

hTNFRSF1B(NM-HU-190010)，hPD-1(NM-HU-00015) and hPD-L1(NM-HU-00062) were crossed together to generate hTNFRSF1B/hPD-1/hPD-L1 mice.

Mice

Ifngr1/Ifnar1-KO

Strain Name：C57BL/6Smoc-Ifngr1em1Ifnar1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190425

This Ifngr1 and Ifnar1 double knockout strain is established by crossing Ifngr1-KO and Ifnar1-KO mice together.

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