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Models

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Mice

Mefv-hMEFV*V726A

Strain Name：C57BL/6Smoc-Mefvtm1(hMEFV-V726A)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200221

Exon 7-10 of the endogenous mouse Mefv gene was replaced by human mutation gene (exon7-10).

Mice

Axl-KO

Strain Name：C57BL/6Smoc-Axlem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-200044

Exon 3 of Axl gene was deleted to generate Axl knockout mice.

Mice

Zbtb46-IRES-Cre

Strain Name：C57BL/6Smoc-Zbtb46em1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200096
Validation Data：Presence

A IRES-iCre expression cassette was knocked into the Zbtb46 gene stop codon site.

Mice

Aqp5-Cre

Strain Name：C57BL/6Smoc-Aqp5em1(iCre-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200062
Validation Data：Presence

A iCre-WPRE-polyA expression cassette was knocked into the Aqp5 gene start codon site.

Mice

Acadm-repeat(E8-10)

Strain Name：C57BL/6Smoc-Acadmem1(E8-10 repeat)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200239

A E8-10 repeat cassette was knocked after exon10 of the Acadm gene.

Mice

Cd19-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Cd19em2(IRES-DTREGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190042
Validation Data：Presence

A IRES-DTREGFP expression cassette was knocked into the Cd19 gene stop codon site.

Mice

Adh7-KO

Strain Name：C57BL/6Smoc-Adh7em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201121

Exon 3 of Adh7 gene was deleted to generate Adh7 knockout mice.

Mice

hAppNL-G-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000088
Validation Data：Presence

The endogenous mouse App gene was replaced by human AppNL-G-F.

Mice

hC5AR1/C5AR2

Strain Name：C57BL/6Smoc-C5ar1tm1(hC5AR1)C5ar2tm1(hC5AR2)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000018
Validation Data：Presence

The endogenous mouse C5ar1 and C5ar2 gene was replaced by human C5AR1 and hC5AR2 gene.

Mice

hGLP1R

Strain Name：C57BL/6Smoc-Glp1rtm2(hGLP1R)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200220
Validation Data：Presence  |  Publications：1piece

The endogenous mouse Glp1r gene was completely or partially replaced by human hGLP1R gene via CRISPR/Cas9 mediated recombination.

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